ID A0A1S8W8F9_9FUNG Unreviewed; 263 AA.
AC A0A1S8W8F9;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE RecName: Full=Mediator of RNA polymerase II transcription subunit 20 {ECO:0000256|RuleBase:RU364152};
DE AltName: Full=Mediator complex subunit 20 {ECO:0000256|RuleBase:RU364152};
GN Name=MED20 {ECO:0000256|RuleBase:RU364152};
GN ORFNames=BSLG_00498 {ECO:0000313|EMBL:OON10766.1};
OS Batrachochytrium salamandrivorans.
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Rhizophydiales;
OC Rhizophydiales incertae sedis; Batrachochytrium.
OX NCBI_TaxID=1357716 {ECO:0000313|EMBL:OON10766.1, ECO:0000313|Proteomes:UP000189906};
RN [1] {ECO:0000313|EMBL:OON10766.1, ECO:0000313|Proteomes:UP000189906}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BS {ECO:0000313|EMBL:OON10766.1,
RC ECO:0000313|Proteomes:UP000189906};
RA Lavstsen T., Jespersen J.S.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC the regulated transcription of nearly all RNA polymerase II-dependent
CC genes. Mediator functions as a bridge to convey information from gene-
CC specific regulatory proteins to the basal RNA polymerase II
CC transcription machinery. Mediator is recruited to promoters by direct
CC interactions with regulatory proteins and serves as a scaffold for the
CC assembly of a functional preinitiation complex with RNA polymerase II
CC and the general transcription factors. {ECO:0000256|RuleBase:RU364152}.
CC -!- SUBUNIT: Component of the Mediator complex.
CC {ECO:0000256|RuleBase:RU364152}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364152}.
CC -!- SIMILARITY: Belongs to the Mediator complex subunit 20 family.
CC {ECO:0000256|ARBA:ARBA00010743, ECO:0000256|RuleBase:RU364152}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OON10766.1}.
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DR EMBL; LYON01000036; OON10766.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1S8W8F9; -.
DR VEuPathDB; FungiDB:BSLG_00498; -.
DR OrthoDB; 2783121at2759; -.
DR Proteomes; UP000189906; Unassembled WGS sequence.
DR GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR InterPro; IPR013921; Mediator_Med20.
DR Pfam; PF08612; Med20; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|RuleBase:RU364152};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364152};
KW Reference proteome {ECO:0000313|Proteomes:UP000189906};
KW Transcription {ECO:0000256|RuleBase:RU364152};
KW Transcription regulation {ECO:0000256|RuleBase:RU364152}.
SQ SEQUENCE 263 AA; 29361 MW; 29B25A1580A38162 CRC64;
MLHARARSRH DEQGVHHTDT WQSVLIHIPS TDLDSVLFAA LTTHLLQGLR CRSNSRWAVN
SRLYIQPPDH QQLVREQRLV YTAHHQGIPD TAPPVQLQSR QLYLVVADHL PKLYSLATFS
DMSRMDEAVP VEGDQELGNI IAKLKNLWTP RQSAVIEGTE YSKKQTIIRL GLVSVGASPR
GMLIHLKIPQ VEGIAMCNTP SGLSASANSL IQGIQKCIAQ VRLDLPMSIH SDKDMNTKSS
AELTDELKEV ALIVRILRLK TIL
//