ID A0A1S8W9X5_9FUNG Unreviewed; 728 AA.
AC A0A1S8W9X5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN ORFNames=BSLG_00117 {ECO:0000313|EMBL:OON11245.1};
OS Batrachochytrium salamandrivorans.
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Rhizophydiales;
OC Rhizophydiales incertae sedis; Batrachochytrium.
OX NCBI_TaxID=1357716 {ECO:0000313|EMBL:OON11245.1, ECO:0000313|Proteomes:UP000189906};
RN [1] {ECO:0000313|EMBL:OON11245.1, ECO:0000313|Proteomes:UP000189906}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BS {ECO:0000313|EMBL:OON11245.1,
RC ECO:0000313|Proteomes:UP000189906};
RA Lavstsen T., Jespersen J.S.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|RuleBase:RU362003}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OON11245.1}.
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DR EMBL; LYON01000007; OON11245.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1S8W9X5; -.
DR STRING; 1357716.A0A1S8W9X5; -.
DR VEuPathDB; FungiDB:BSLG_00117; -.
DR OrthoDB; 2712461at2759; -.
DR Proteomes; UP000189906; Unassembled WGS sequence.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016866; F:intramolecular transferase activity; IEA:InterPro.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR Gene3D; 6.20.120.20; -; 1.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF20; LANOSTEROL SYNTHASE; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|RuleBase:RU362003};
KW Reference proteome {ECO:0000313|Proteomes:UP000189906};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 84..326
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 386..719
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 728 AA; 82094 MW; 7A1F22F50E187219 CRC64;
MTADYSQDST AGDAATITGA TDLLRWRLRV DHGAQTWHYL ETAEECAAWP QTAYDKYWLG
ILQDKTVFKQ PSTALDAARN GLRFFRQLQT PDGHFAGEYG GPMFLIPGLV IAMYISGASY
PPGYVEELIR YLKTTANKDD GGWGIHIEGV STCFGTSLNY VALRLLGSPA NDPVCVKARD
TLWKLGGACG VPAWGKFWLS VLNVYDWSGN SPIPPELWIL PYMAPVHAGR MWCHTRMVYL
PMGYLYGIRF QAKVDDLILS LREELYTCDY SAINWPQQCN NVAAVDIYSP HSSFLDIFTG
LAGIYESLPN GILRSRALDE VLLQIRMEDK NTNFLDLGPV NKAINLLVSF VVDGPTSDNF
KRHVERVPDF MWMSDRGMMM NGTNGSQLWD TAFAVQSILE SNLGQEPEFH DMISRAYAFV
DDMQIKRNAE NHERCYRHIS KGAWPFSTQE QSYTVSDCTA EGLKGVLMVH NKLKSIKPTI
SEERLFDAVN VLLSMQNSNG GFASYELQRG SELLEILNPS EVFGKIMVEY SYTECTTSVL
LGLSSFRKTY PYHRAKEIDE TVDRAVNFIR KLQLPNGLWF GSWGVCFTYA TFFAVESLSS
VGETYKSSDS LRSACDGLVE KQMWDGGWGE SYRTCETGVW VNHKQSQVVQ TAWALMSLMA
AKYPMPSPIK KGIALIMSRQ LPNGEWPQEA IEGVFNKNCM ISYPNYKFVF PIWALGRYSR
YYETTSES
//
