ID A0A1S9A8D7_9BURK Unreviewed; 823 AA.
AC A0A1S9A8D7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
DE AltName: Full=Beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00030512};
DE AltName: Full=N-acetyl-beta-glucosaminidase {ECO:0000256|ARBA:ARBA00033000};
GN ORFNames=B0920_20605 {ECO:0000313|EMBL:OON59689.1};
OS Massilia sp. KIM.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Telluria group; Massilia.
OX NCBI_TaxID=1955422 {ECO:0000313|EMBL:OON59689.1, ECO:0000313|Proteomes:UP000190838};
RN [1] {ECO:0000313|EMBL:OON59689.1, ECO:0000313|Proteomes:UP000190838}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM {ECO:0000313|EMBL:OON59689.1,
RC ECO:0000313|Proteomes:UP000190838};
RA Vikram S., Kabwe M.H., Bezuidt O., Govender N., Makhalanyane T.P.;
RT "Genome sequence of Massilia sp. KIM isolated from grassland biome soil in
RT South Africa.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OON59689.1}.
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DR EMBL; MVAD01000003; OON59689.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1S9A8D7; -.
DR STRING; 1955422.B0920_20605; -.
DR OrthoDB; 9763537at2; -.
DR Proteomes; UP000190838; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd02847; E_set_Chitobiase_C; 1.
DR Gene3D; 2.60.40.290; -; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR008965; CBM2/CBM3_carb-bd_dom_sf.
DR InterPro; IPR012291; CBM2_carb-bd_dom_sf.
DR InterPro; IPR004866; CHB/HEX_N_dom.
DR InterPro; IPR004867; CHB_C_dom.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF03173; CHB_HEX; 1.
DR Pfam; PF03174; CHB_HEX_C; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SMART; SM01081; CHB_HEX; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR SUPFAM; SSF49384; Carbohydrate-binding domain; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000190838}.
FT DOMAIN 14..156
FT /note="Chitobiase/beta-hexosaminidases N-terminal"
FT /evidence="ECO:0000259|SMART:SM01081"
FT ACT_SITE 493
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 823 AA; 89756 MW; 9B9DBE50E7059B27 CRC64;
MKPIPEPSSR PGAAPVAVSW ECLTNTARDD RFRARLVLAN VSDAAIAPGW RLYFNTARKP
LAASATPGYA IEHLNGDLCR LGMPDGGPWL PGQRHVIDYD CLHWAISVTD APLGFHLVTA
EGEAIDLGDP RIAPFARPEQ RMRTSYDLLP TEDAARRHRR NAGLRQLPED EIGRITPRPV
HARLGGATCR LSPGAPLVHD ASLGREAALL SAMLAALPDG PPGEAGVELR LGAVALEDPS
EEAYELEIGA RRVCVRGRSA HGVFNGLQTL AQLLGPDGSL PLGQVLDAPR FAYRGMMLDV
ARHFSSVATV LRLLDCMAAY KLNRFHFHLT DDEGWRLAIA ALPELTAIGS RRGVGASCLP
PSYGSGARIE GSAGTGFYSA EEFVAILRHA HARHIEVIPE FNMPGHARAA VVAMRARYER
LLAAGDRAGA EEYLLSDPDD RSEYESVQLW HDNVICIALP SVDRFIDTVV GEVCALYREA
GAPLRVIHTG GDEVPAGAWL GSPLCRAKME REGWTRIDQL HDDFVARCRA ILARHGLGFA
GWEETALVEV TGEGMRPNPR FAGPDFHAYV WNNAWGSGQE DCAYRLANAG YRVVLANAAN
LYFDLAYAKH PEEPGYYWAG FVETRHAFAF CPLDVRVTAD LDPLGRPLDP RVLAAMQPLD
AAGKERIAGL QGQLWGENAV DAGRIDYLAL PRLIALAERA WSPDPGWQHV ADEAQRAAAI
ERDWNEFANR LARRELPRLD RAPEPYRYRL PPPGVALQDG AAHANVALPG LALHYTVDGS
EPSASGPRYQ APVPLAPGSR FRIASFDTRG RRSRIVSLIL DTP
//
