ID A0A1S9AFE3_9BURK Unreviewed; 619 AA.
AC A0A1S9AFE3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Signal peptide peptidase SppA {ECO:0000313|EMBL:OON62180.1};
GN ORFNames=B0920_01430 {ECO:0000313|EMBL:OON62180.1};
OS Massilia sp. KIM.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Telluria group; Massilia.
OX NCBI_TaxID=1955422 {ECO:0000313|EMBL:OON62180.1, ECO:0000313|Proteomes:UP000190838};
RN [1] {ECO:0000313|EMBL:OON62180.1, ECO:0000313|Proteomes:UP000190838}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM {ECO:0000313|EMBL:OON62180.1,
RC ECO:0000313|Proteomes:UP000190838};
RA Vikram S., Kabwe M.H., Bezuidt O., Govender N., Makhalanyane T.P.;
RT "Genome sequence of Massilia sp. KIM isolated from grassland biome soil in
RT South Africa.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S49 family.
CC {ECO:0000256|ARBA:ARBA00008683}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OON62180.1}.
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DR EMBL; MVAD01000001; OON62180.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1S9AFE3; -.
DR STRING; 1955422.B0920_01430; -.
DR OrthoDB; 9764363at2; -.
DR Proteomes; UP000190838; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR CDD; cd07018; S49_SppA_67K_type; 1.
DR CDD; cd07023; S49_Sppa_N_C; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR004634; Pept_S49_pIV.
DR InterPro; IPR004635; Pept_S49_SppA.
DR InterPro; IPR002142; Peptidase_S49.
DR InterPro; IPR047217; S49_SppA_67K_type_N.
DR InterPro; IPR047272; S49_SppA_C.
DR NCBIfam; TIGR00705; SppA_67K; 1.
DR NCBIfam; TIGR00706; SppA_dom; 1.
DR PANTHER; PTHR33209; PROTEASE 4; 1.
DR PANTHER; PTHR33209:SF1; SERINE PROTEASE SPPA, CHLOROPLASTIC; 1.
DR Pfam; PF01343; Peptidase_S49; 2.
DR PIRSF; PIRSF001217; Protease_4_SppA; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000190838};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825}.
FT DOMAIN 137..288
FT /note="Peptidase S49"
FT /evidence="ECO:0000259|Pfam:PF01343"
FT DOMAIN 389..539
FT /note="Peptidase S49"
FT /evidence="ECO:0000259|Pfam:PF01343"
FT ACT_SITE 204
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001217-1"
FT ACT_SITE 405
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR001217-1"
SQ SEQUENCE 619 AA; 67080 MW; ED0401DA32DEB006 CRC64;
MAFKPFSALR RGVVWLWSAL DATRRTFFNL LFLLFLIVLL WMVFGGGGVK PIAGNTALVL
ELKGDLVEQY QANLRETVLD SVGGDSKRTV RLRDVLVVLE KAAEDPNIST VVLLLDEMEG
GGLAMLREFG AAIDKVKAGG KKVVAWSGNY DQKRYLVASH ADEVYVHPMG MVLIEGFGRH
KNYYRDALDK LGVTVNLMKV GTYKSFAEPF IANGPSDAAR EADAYLFNAL WAGYTGEIEK
NRRLEGGAVA RLIDTLPQQM EAAGGNAAKV ALANKLVDGL KTRDEMRAML IKRGVYEESY
KSFRQVGFYD YLSRHQQKPF GDAVGVIVAA GNITEGLGGP GVVGGLTTAN LIRQAREDDE
IKAVVLRVDS PGGSAYGSEL IRRELELTRA AGKPVVVSMG STAASGGYWI AMAADEIIAD
PYTVTGSIGV FAILPTADKV RDKLGIHTEG VTTTWLADAY NPLRPLDPRF GQLVQSSINH
VYNEFTTKAA AARKTTPAKI DEVGQGRVWT GAQAKDRGLV DRLGGYRDAL DSAARRAKLD
GDYRVAYIER PVNRIERFLQ MMGASAAQAV NIQVKLGLLE EALPAGPVAQ VAEDMAFLSE
LSEGRKPFAA VTHCLCASP
//
