ID A0A1S9CEY2_9FIRM Unreviewed; 524 AA.
AC A0A1S9CEY2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Sodium:proton antiporter {ECO:0000313|EMBL:OON95255.1};
GN ORFNames=ATN31_11355 {ECO:0000313|EMBL:OON95255.1};
OS Epulopiscium sp. AS2M-Bin001.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Candidatus Epulonipiscium.
OX NCBI_TaxID=1764958 {ECO:0000313|EMBL:OON95255.1, ECO:0000313|Proteomes:UP000190284};
RN [1] {ECO:0000313|EMBL:OON95255.1, ECO:0000313|Proteomes:UP000190284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AS2M-Bin001 {ECO:0000313|EMBL:OON95255.1};
RA Seilhamer J.J.;
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OON95255.1}.
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DR EMBL; LNZM01000073; OON95255.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1S9CEY2; -.
DR STRING; 1764958.ATN31_11355; -.
DR Proteomes; UP000190284; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR PANTHER; PTHR43478; NA+/H+ ANTIPORTER-RELATED; 1.
DR PANTHER; PTHR43478:SF1; NA_H_ANTIPORTER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000190284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 464..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 487..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 189..483
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 524 AA; 55419 MW; FCAF98D2043458FE CRC64;
MLEAIDVGVL SLLPPIIAIG LALITKEVIS SLLIGILSGT FIYAYNTGGD LLSNLIETID
ITVRLSAEKI GANASIIIFL ALLGALVAIV TKAGGSKAYG EWASKKIKSK RGASLATSAL
GAMIFIDDYF NCLTVGTVMR PVTDKHNISR PKLAYIIDAT AAPICIIAPI SSWAASVISQ
LDDVGLDGMS AFVQLIPFNF YAILTIVMVL TLSITNLDFG SMKKFELDAA NNLNAENKNL
THTGDELKDM QISEKGKVTD LVIPVLCLIV FCTLSMLYVG GYFNGGMTLA QGFGNTDAGM
SLALGSFLTL IATFILLIPR RVITFTQFMD GISTGIKTMV PAFIILTLAW TISGVCRDLL
LTGPYVGGLV ESSNLPPALL PAIIFIVASI LAFSTGTSWG TFGILIPIVA DALSSVAPEL
LIVSLSATLA GAVLGDHMSP ISDTTILSST GAGCNHIDHV RTQIPYVMLV GFACVIGYLF
AGLTNNFFIS FIAALSVLIS TLVFMNKLNN KHNKQTIENA VALD
//
