ID   A0A1S9DF80_ASPOZ        Unreviewed;       318 AA.
AC   A0A1S9DF80;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Tyrosinase {ECO:0000313|EMBL:OOO07715.1};
GN   ORFNames=OAory_01042150 {ECO:0000313|EMBL:OOO07715.1};
OS   Aspergillus oryzae (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=5062 {ECO:0000313|EMBL:OOO07715.1, ECO:0000313|Proteomes:UP000190312};
RN   [1] {ECO:0000313|EMBL:OOO07715.1, ECO:0000313|Proteomes:UP000190312}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCC7051 {ECO:0000313|EMBL:OOO07715.1,
RC   ECO:0000313|Proteomes:UP000190312};
RA   Thammarongtham C., Vorapreeda T., Nookaew I., Srisuk T., Land M.,
RA   Jeennor S., Laoteng K.;
RT   "Genome sequencing of Aspergillus oryzae BCC7051.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OOO07715.1}.
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DR   EMBL; MKZY01000006; OOO07715.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1S9DF80; -.
DR   VEuPathDB; FungiDB:AO090010000557; -.
DR   eggNOG; ENOG502S31Y; Eukaryota.
DR   OMA; SLWAPDF; -.
DR   Proteomes; UP000190312; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF141; N-ACETYL-6-HYDROXYTRYPTOPHAN OXIDASE IVOB-RELATED; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   PRINTS; PR00092; TYROSINASE.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   PROSITE; PS00497; TYROSINASE_1; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190312}.
FT   DOMAIN          88..105
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00497"
FT   DOMAIN          236..247
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
SQ   SEQUENCE   318 AA;  36232 MW;  3ABF113D5451A886 CRC64;
     MSSNVDKRET VSQFIPEYFT GSCSKEKMTI RKEWRHLTAK QQTSFLDAVQ CLMDKPAKSG
     LTATTSRFSD LQALHRGMTN TAHADIIHHV GQFLPWHRYY MHIYETLLRE ECSYTGPIPW
     WDEQKDADSG NMWQSSMWGP DAFGGNGTGS DLCVIDGRFS NYTLHIGPGD EDTDYCLRRA
     WDNENAIANA NSTALNNCNA YNTFSPWWDC ISNIPHKGIH TYIGGVMADI KSSPGDPIFF
     MHHMYIDRVW WKWQKEDPIN RLYDISGPTL NHTANVEPAG GWQNATLHYE LSSFNIKPNV
     TIGEVMNTQG GYLCYGYD
//