ID   A0A1S9DLS8_ASPOZ        Unreviewed;      1243 AA.
AC   A0A1S9DLS8;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=DUF726 domain protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=OAory_01058290 {ECO:0000313|EMBL:OOO10021.1};
OS   Aspergillus oryzae (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=5062 {ECO:0000313|EMBL:OOO10021.1, ECO:0000313|Proteomes:UP000190312};
RN   [1] {ECO:0000313|EMBL:OOO10021.1, ECO:0000313|Proteomes:UP000190312}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCC7051 {ECO:0000313|EMBL:OOO10021.1,
RC   ECO:0000313|Proteomes:UP000190312};
RA   Thammarongtham C., Vorapreeda T., Nookaew I., Srisuk T., Land M.,
RA   Jeennor S., Laoteng K.;
RT   "Genome sequencing of Aspergillus oryzae BCC7051.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TMCO4 family.
CC       {ECO:0000256|ARBA:ARBA00009824}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OOO10021.1}.
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DR   EMBL; MKZY01000004; OOO10021.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1S9DLS8; -.
DR   VEuPathDB; FungiDB:AO090003000974; -.
DR   eggNOG; KOG2385; Eukaryota.
DR   Proteomes; UP000190312; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR007941; DUF726.
DR   PANTHER; PTHR17920:SF24; LIPASE MIL1-RELATED; 1.
DR   PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR   Pfam; PF05277; DUF726; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190312};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        649..674
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..319
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          501..558
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1044..1064
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1089..1151
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        93..137
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..171
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        194..216
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        265..281
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        282..300
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        510..538
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1092..1143
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1243 AA;  134957 MW;  582FFA0D471BF11D CRC64;
     MSGLPDLSHK EPSAQTLMEQ ARSRADNARE DLSNPHAEPV AGVQTDQSRN ARQDLDKGGT
     AKTSVEGGHS SRIATVDYSR DPAVDHSQAV SHEPEHSQTA AAENSTGSPD IKSQKENASP
     VGGNAGSEPT TESTTGEVDE FGLPIRIRAR PVRSSESSDN EEFHDVEEAA SGPADKQPTS
     QDSKPVMNEI KLEAPQEEST KPVDKGKDEE KGTESLPAVE PHSVESPREK DSSVPVGNEK
     HATSSGSLPD QEDCPPPPPY TEKPNAGNPS TSTQSDAVQK KRSSLKASEW SHQRLNESKD
     SEDEDEAESD GGWQDMPAID EFDVYDDYGR LVARGAKPED NDAVYKGLGG AGKGYTRVQL
     DEDAQSATSL DEDTSYLFRE AAHNSTGVEG EELRDAVSQL QATKDLLTES QRIAYVGVTR
     LAIFQMTRDL DRVPSTKGTR KAKQKTIDSM RKWGQTIMAR IYAHMDIDAA EQVMIEQLAE
     HGVQPADLVR PLMQNARVKN PLAEELDTPK KSLSSPTTPS LKDEYRSSLS SDFDRSTSPP
     PYETHEGEDL PEVRTPSQLP TSTKIDIDLR WTVLCDLFLV LIADSAYDAR SRSLLEKVGE
     SMEVSWLQIA RFEKRVVDAL EMQEEADKET WDESDHMERR RKMALKRKYI VMGLATVGGG
     LVIGLSAGLL APVIGAGLAA GFTTVGISGT GAFLGGVGGT AIIASGGTLT GGTIGLRASN
     RRTGAVQTFE YRPLHNNKRV NLIVTVSGWM TGKVDDVRLP FSTVDPIMGD LYSVLWEPEM
     LRSMGDTINI LATEALTQGL QQVLGSTVLV ALMSSLQLPL VLTKLSYLID NPWIVSLARA
     NAAGLIMADS LMERNLGKRP VTLLGFSLGS RLIFSCLKEL ADRGAHGLVQ NVYLFGSPIV
     ANKDEYLKAR SVVSGRFVNG YSSNDWILGY LFRATSGGIM RVAGLAPVEG IPGLENFDVT
     KLVNGHMDYR AAMPRLLKEV GWEVLGDEFA ELEDPDPENH AERQRELIRE IDEARREAEA
     KPEKKRFGLF KRGKLAQKKG WETYDVERNN ATPRDSSDSN GTGSVLFDID AIRAELASES
     IEVKQLESTL PPMKLDLNSP SSSTPVTPTP SDSKDTTKAV NLTKSAPQSP PEPYSVPSAS
     HDQQPSTHKE DEEIEMTFDT SYHEPLQRSH SFFEPTTATS YDAHSTRPEL RSSSTTPAGL
     GIGAAAGVGV GASALGALAL EPNAWADHDI GDGEEGEIHM SFE
//