ID   A0A1S9DP25_ASPOZ        Unreviewed;       429 AA.
AC   A0A1S9DP25;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:OOO10835.1};
GN   ORFNames=OAory_01073050 {ECO:0000313|EMBL:OOO10835.1};
OS   Aspergillus oryzae (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=5062 {ECO:0000313|EMBL:OOO10835.1, ECO:0000313|Proteomes:UP000190312};
RN   [1] {ECO:0000313|EMBL:OOO10835.1, ECO:0000313|Proteomes:UP000190312}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCC7051 {ECO:0000313|EMBL:OOO10835.1,
RC   ECO:0000313|Proteomes:UP000190312};
RA   Thammarongtham C., Vorapreeda T., Nookaew I., Srisuk T., Land M.,
RA   Jeennor S., Laoteng K.;
RT   "Genome sequencing of Aspergillus oryzae BCC7051.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00038048}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OOO10835.1}.
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DR   EMBL; MKZY01000003; OOO10835.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1S9DP25; -.
DR   VEuPathDB; FungiDB:AO090012000011; -.
DR   Proteomes; UP000190312; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR12286:SF5; SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR12286; UNCHARACTERIZED; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190312};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        282..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          10..138
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
SQ   SEQUENCE   429 AA;  48017 MW;  952830DFEB82746C CRC64;
     MTSRRQYDLI LLGATGYTGM LTTQYIFKSL PLDLKWAIAG RNRGKLEQLA QSLMPENSSR
     QPPDILVVNL NEKELNGLAK RTRLVISTVG PFLLYGSETF AACARNGTHY LDCNGEIPWL
     KNMIQQYDRT AKETGSIMIP CCGFDCVPSD LSTWLAASYI RRHFNAQTGR VDVCIHGVQS
     GVSGGTLASV LQAFELHSLR HLYKAHAPYS LSPRQPSPTV PTKPTSIWTK LFGLLWIKRL
     GWMAYQPQGP VDRAIVHRSW GLLESTTVSY GQNFDFHAWF KIWGPVAAIL WHFGGLMLAP
     LILLRPIRKL LPKLWYEPGG GAGQSDIENN WFEYRCVAEA DTPTKPKQKA LVRMRYESDP
     YIFTAVALGE AARILLWQKD TWAHKFGGGV LTSATLGDHY VSRLRAAGVT MEVQADDPVY
     KGKDPFTKV
//