ID   A0A1S9DYI7_ASPOZ        Unreviewed;       990 AA.
AC   A0A1S9DYI7;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:OOO14125.1};
GN   ORFNames=OAory_01027200 {ECO:0000313|EMBL:OOO14125.1};
OS   Aspergillus oryzae (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=5062 {ECO:0000313|EMBL:OOO14125.1, ECO:0000313|Proteomes:UP000190312};
RN   [1] {ECO:0000313|EMBL:OOO14125.1, ECO:0000313|Proteomes:UP000190312}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BCC7051 {ECO:0000313|EMBL:OOO14125.1,
RC   ECO:0000313|Proteomes:UP000190312};
RA   Thammarongtham C., Vorapreeda T., Nookaew I., Srisuk T., Land M.,
RA   Jeennor S., Laoteng K.;
RT   "Genome sequencing of Aspergillus oryzae BCC7051.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OOO14125.1}.
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DR   EMBL; MKZY01000001; OOO14125.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1S9DYI7; -.
DR   VEuPathDB; FungiDB:AO090023000547; -.
DR   VEuPathDB; FungiDB:AO090023000549; -.
DR   VEuPathDB; FungiDB:AO090023000550; -.
DR   eggNOG; KOG1176; Eukaryota.
DR   Proteomes; UP000190312; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR005000; Aldolase/citrate-lyase_domain.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR   PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR   PANTHER; PTHR43201:SF8; FATTY ACID COA SYNTHETASE FAMILY; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF03328; HpcH_HpaI; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:OOO14125.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190312}.
FT   DOMAIN          92..286
FT                   /note="HpcH/HpaI aldolase/citrate lyase"
FT                   /evidence="ECO:0000259|Pfam:PF03328"
FT   DOMAIN          465..813
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
SQ   SEQUENCE   990 AA;  110077 MW;  44E51E0906E96E75 CRC64;
     MAGCTNLSAI NIGTPGCDIK RDLKREVSFS DLKLTSVTLM TAPAFFESTL RKETKMLNTK
     DYNAMSLAQP TNFKAMLNSG QFLWGTGCRI PHPEAARIIA ATPFHFCFLD AEHAPLNATL
     LVSLVRTIQY QSNGCMVPFV RIPRCSPELY NYILGAGAGG VVMPHIQNAK QAEELVRLCR
     FPPMGDRSFP PAALIGEQQN RTPIGQSTYD VWDSHVAVFC QIEDLEGLEN VEEICKVPGV
     DGLFIGTGDL RMCMKLSHGS LDGDEPVYLA ALKKIRDAAK VNNLPIMGFG ISPAALQLRI
     DMGWNAFIIH GDIDAICTSA TDSLQTYTNA AGEKMASLES DVKALLAREL EVPIHEVTTT
     ADLKKDLTVN DLGKSQMINA IRERFDVYIE EEDTDQLNTS MSNINWYEKP TANRRLAFAT
     AHDVINHPKA MTIQDKPTFP DDVLFRRLID IAIERDSKTI VDDYSTGTQF GYRQILHGIA
     KLQQTLQGLL HLSESRKPGS VYVALLAPNG YEFIVGVIAV LAVGGVVVPM PTGALPAEAA
     YIIQQCNAQV MIVSRELTES ATQIQREVEI PSITIEGNTH TSSNLPPAGS YRLDSTLAVS
     EETPSILFFT SGTTGPPKGV LHSRRTINKY AHMETEPATN DDICIIPRGA FWSIYFTKLF
     QMLLAGVRVE IQNFGRNYNL IWERLREQAG TKIVLSPTFW YGMMLHYESH ISKLPEQVIQ
     DYIDGVRYIR DACATGAMPS SRVKQFWQEM RGGKPLRVLY GSTETQEIAM WDGAIGSEEA
     DLGTPFPHVT MKLSEGDQGE LLVKTPSMFL GYLNSPDATA KRLDAEGFFK TGDLATLENG
     RFIFKGRANM DLFKFFTYKV PRMEVEAKLT ALPYVSEGYI LPVQDPQCDT RTAALVRFHD
     SYDKIDLGSL RRDLAHDLPA YQLPTVLRSL REGETVPRTW SDKTAMMKVI QMFFPQDTED
     KICGDATEVM DVSGFMKMKT TKLWELSGIR
//