ID   A0A1T0AQE4_9PAST        Unreviewed;       420 AA.
AC   A0A1T0AQE4;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Acylneuraminate cytidylyltransferase {ECO:0000313|EMBL:OOR98185.1};
GN   ORFNames=B0187_09600 {ECO:0000313|EMBL:OOR98185.1};
OS   Haemophilus paracuniculus.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=734 {ECO:0000313|EMBL:OOR98185.1, ECO:0000313|Proteomes:UP000190867};
RN   [1] {ECO:0000313|EMBL:OOR98185.1, ECO:0000313|Proteomes:UP000190867}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCUG 43573 {ECO:0000313|EMBL:OOR98185.1,
RC   ECO:0000313|Proteomes:UP000190867};
RA   Engstrom-Jakobsson H., Salva-Serra F., Thorell K., Gonzales-Siles L.,
RA   Karlsson R., Boulund F., Engstrand L., Kristiansson E., Moore E.;
RT   "Draft genome sequence of Haemophilus paracuniculus CCUG 43573 type
RT   strain.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OOR98185.1}.
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DR   EMBL; MUYA01000018; OOR98185.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T0AQE4; -.
DR   STRING; 734.B0187_09600; -.
DR   OrthoDB; 9805604at2; -.
DR   Proteomes; UP000190867; Unassembled WGS sequence.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:UniProt.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR   CDD; cd02513; CMP-NeuAc_Synthase; 1.
DR   Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR   InterPro; IPR003329; Cytidylyl_trans.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR013830; SGNH_hydro.
DR   InterPro; IPR036514; SGNH_hydro_sf.
DR   PANTHER; PTHR21485; HAD SUPERFAMILY MEMBERS CMAS AND KDSC; 1.
DR   PANTHER; PTHR21485:SF3; N-ACYLNEURAMINATE CYTIDYLYLTRANSFERASE; 1.
DR   Pfam; PF02348; CTP_transf_3; 1.
DR   Pfam; PF13472; Lipase_GDSL_2; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR   SUPFAM; SSF52266; SGNH hydrolase; 1.
PE   4: Predicted;
KW   Nucleotidyltransferase {ECO:0000313|EMBL:OOR98185.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190867};
KW   Transferase {ECO:0000313|EMBL:OOR98185.1}.
FT   DOMAIN          267..409
FT                   /note="SGNH hydrolase-type esterase"
FT                   /evidence="ECO:0000259|Pfam:PF13472"
SQ   SEQUENCE   420 AA;  48287 MW;  ECA1BA4BE4F7D992 CRC64;
     MKKIAIITAR AGSKGLPNKN VLLVEGKPLM AYSIEAALES GEFDKIIVST DSQEYIDLLS
     HYPIEFIKRA EHLATDTTSS FAVIEDVLQQ YQGVDFDYFV LLQPTSPLRN GQHIREACQK
     FEQHFTQFDF LVSVSDAHKP TTLTRQIDGD ESLKNFQLDY SNYARQQYHP EYSPNGAIFC
     AKPTAYLVQK HFYGEKSLAY FMDKAVSIDI DDRNDFEYFY FVMQQRNRIQ TMLNTIKQRI
     EYKKPQFNLA KPITLIGHSI LDQWQIETLN GQAVNNLGFS GIATKEYFDL ILDQGLIQQL
     GEQVVLMLGV NDFTRSNWTF EQIRADLQQV IDKILQIRAD CQIFFLEVTP SAFRVNLNNA
     EIRELNQLLK QKLTNVKWVD LDEAFSDKYG KLDLALSHDG LHFNAKGYEK LAAILEKELA
//