ID A0A1T1AUE8_RHOFE Unreviewed; 578 AA.
AC A0A1T1AUE8;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Sensor domain-containing diguanylate cyclase {ECO:0000313|EMBL:OOV07605.1};
GN ORFNames=RF819_13455 {ECO:0000313|EMBL:OOV07605.1};
OS Rhodoferax fermentans.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Rhodoferax.
OX NCBI_TaxID=28066 {ECO:0000313|EMBL:OOV07605.1, ECO:0000313|Proteomes:UP000190750};
RN [1] {ECO:0000313|EMBL:OOV07605.1, ECO:0000313|Proteomes:UP000190750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 7819 {ECO:0000313|EMBL:OOV07605.1,
RC ECO:0000313|Proteomes:UP000190750};
RA Kim Y.J., Farh M.E.-A., Yang D.-C.;
RT "Genome sequencing of Rhodoferax fermentans JCM 7819.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OOV07605.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MTJN01000002; OOV07605.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T1AUE8; -.
DR STRING; 28066.RF819_13455; -.
DR OrthoDB; 9813903at2; -.
DR Proteomes; UP000190750; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd12913; PDC1_MCP_like; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR029151; Sensor-like_sf.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR PANTHER; PTHR46663:SF2; GGDEF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000190750};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 366..418
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 445..578
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 578 AA; 63840 MW; 10AA99885C43CF9B CRC64;
MNLYSSLTLR QWLTVPFTVL MVGVVVLTGA LSYSTGSQAV NTVSQHLLQE MVARVGQAVN
RHVVGSAAVL EAAFPTGLEV PDTIDAELDT LRTRFWIATS LHTDPNNFVY YGNQHGQAIG
LLRLSSDEAE LRYKLRADEF RGFSRFSGIN GALGPKTFEK KLFDPRERPW YKAAERSLSS
AWSAIYIDFT TEELVATRAR RVLDAQGELQ GVVATDISLQ RLNLFVSNLP ISSHGVAFII
EPDGKLIASS SGPNIKRLPG GGSERLMAID SVNPLQRAAY QQVRDRLQSA SLGVGPRALA
FDGPNGETVE MAFDRVLDQA GLYWLIVVAV PRSDFMQGIT ANIFRTALIG LLGVIAAVVL
GWRIVGWVDR DIKRLTEAAK LVGEGRLGAP LEVYRNDEIG VLASTFRKMQ YRLRTDVLTG
LSNREMLLHS ITQRIEHKRR ERDALSFALL FVDLNNFKLI NDHLGHDAGD RVLMEIATRL
SKVVRPGDVV ARYAGDEFVL LINDIPSRQV ADQVRRKLEA TLLEPVQQVD LGSVPDGAGF
GGAVGLAMYP MDGDTAELLI ARADQEMYER KRAWRLDA
//
