ID A0A1T1AV83_RHOFE Unreviewed; 915 AA.
AC A0A1T1AV83;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=RF819_16015 {ECO:0000313|EMBL:OOV08026.1};
OS Rhodoferax fermentans.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Rhodoferax.
OX NCBI_TaxID=28066 {ECO:0000313|EMBL:OOV08026.1, ECO:0000313|Proteomes:UP000190750};
RN [1] {ECO:0000313|EMBL:OOV08026.1, ECO:0000313|Proteomes:UP000190750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 7819 {ECO:0000313|EMBL:OOV08026.1,
RC ECO:0000313|Proteomes:UP000190750};
RA Kim Y.J., Farh M.E.-A., Yang D.-C.;
RT "Genome sequencing of Rhodoferax fermentans JCM 7819.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OOV08026.1}.
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DR EMBL; MTJN01000002; OOV08026.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T1AV83; -.
DR STRING; 28066.RF819_16015; -.
DR OrthoDB; 9806130at2; -.
DR Proteomes; UP000190750; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF13492; GAF_3; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OOV08026.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000190750};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 447..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 472..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 497..514
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 690..910
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 915 AA; 99357 MW; DB5AAD90A5C69BBB CRC64;
MPLSTDARPD PDVLLAQLRE EEQTVKRGTL RIYFGASAGV GKTYALLGAA RQAQQAGHKV
LVGVVETHGR QETQALLADL TLLPLRKLPH RGQVLLELDL DAALAAKPDI LLVDELAHSN
APGSRHPKRW QDVQELLDAG INVWSALNVQ HLESLNGTVG AITGVRVNET VPDTVLDDAD
ELVLVDVTAE ELLARLKAGK VYIPQQAQRA SQNFFRKGNL IALREIALRR TAEHVGDDVR
TYRTRHTQKT LSSQTSGTPA WNTSGAMLVC VGPQAGAEHA VRSAARLAGQ LNVRWFAAYV
ETPALQRRPA PERDRVLTVL KLAEELGAST AVLTGEDEAQ ALMTHAQTLN CATLVLGRPA
SSHWRQLRRI WRPTLARQLA TLAPGIDLVE VGASESVRKL PPALPRPVQD ETQGHNWVED
MPRYAWATGI CLLTTLFALP LARLFDLANI VMLFLLCVVL VAVKLGRGPS MLAAVLSVAV
FDFFFVQPRF SFAVTDIQYL MTFFVMLVVG LLIGRLTANL RFAAQVAASR EQRAQALFEL
TRDLSGALLT SQVVESAESL VSRAFGGEAR VLLPDANDQL DCGAHLPTSL DTSVADWAFR
HGQRAGAATA TLPGSSWHFV PLQAPMRIRG VLAVRVPKPR WLLIPEQIQQ LETLARQIAI
ALERVHYVDV AQAAVVQMES ERLRNTLLAA MSHDIRTPLT ALVGQAEVLA ASTPLNPEQR
SSAQTISQEA RELSSLVTNM LEMARLQSGQ VELRKDWQSV EEIVGSAIRS ARHALGALVV
RTELPVDLPL VEFDASLIER VLVNLLENAA KYGVTTPPAN PAMVVSASVT PNTLVVSVRD
FGPGLPHHVK GREDELFAKF TRGHHESSTR GVGLGLAICK AIIDAHRGKI SAAQAADAGA
IFSFSLPRNS PPEVP
//
