ID A0A1T1H8I0_OCELI Unreviewed; 1036 AA.
AC A0A1T1H8I0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=type I site-specific deoxyribonuclease {ECO:0000256|ARBA:ARBA00012654};
DE EC=3.1.21.3 {ECO:0000256|ARBA:ARBA00012654};
GN ORFNames=BTA35_0214315 {ECO:0000313|EMBL:OOV86153.1};
OS Oceanospirillum linum.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Oceanospirillum.
OX NCBI_TaxID=966 {ECO:0000313|EMBL:OOV86153.1, ECO:0000313|Proteomes:UP000190064};
RN [1] {ECO:0000313|EMBL:OOV86153.1, ECO:0000313|Proteomes:UP000190064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11336 {ECO:0000313|EMBL:OOV86153.1,
RC ECO:0000313|Proteomes:UP000190064};
RA Trachtenberg A.M., Carney J.G., Linnane J.D., Rheaume B.A., Pitts N.L.,
RA Mykles D.L., Maclea K.S.;
RT "Draft Genome Sequence of the Salt Water Bacterium Oceanospirillum linum
RT ATCC 11336.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endonucleolytic cleavage of DNA to give random double-stranded
CC fragments with terminal 5'-phosphates, ATP is simultaneously
CC hydrolyzed.; EC=3.1.21.3; Evidence={ECO:0000256|ARBA:ARBA00000851};
CC -!- SIMILARITY: Belongs to the HsdR family.
CC {ECO:0000256|ARBA:ARBA00008598}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OOV86153.1}.
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DR EMBL; MTSD02000008; OOV86153.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T1H8I0; -.
DR STRING; 966.BTA35_0214315; -.
DR REBASE; 203500; Oli11336ORF214320P.
DR Proteomes; UP000190064; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0009035; F:type I site-specific deoxyribonuclease activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR CDD; cd22332; HsdR_N; 1.
DR Gene3D; 3.90.1570.50; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR007409; Restrct_endonuc_type1_HsdR_N.
DR InterPro; IPR040980; SWI2_SNF2.
DR PANTHER; PTHR30195:SF15; TYPE I RESTRICTION ENYME HINDI ENDONUCLEASE SUBUNIT; 1.
DR PANTHER; PTHR30195; TYPE I SITE-SPECIFIC DEOXYRIBONUCLEASE PROTEIN SUBUNIT M AND R; 1.
DR Pfam; PF04313; HSDR_N; 1.
DR Pfam; PF18766; SWI2_SNF2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000313|EMBL:OOV86153.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000190064};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747}.
FT DOMAIN 300..476
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
SQ SEQUENCE 1036 AA; 120169 MW; 873220AC4716E586 CRC64;
MKFNEDSRVK IPAILHLMRL GYQYLSLKDQ SWDLDTNIFP AIFKAAIGKI NPGIEAAEAG
RLLEDVKLLL DNEDLGKAFF ERLSERSNTK LIDFESFNNN TFHVVTELTC QNGDEEFRPD
ITLLINGMPL VFIEVKKPNN REGILAERDR INKRFQNPKF KRFANITQFM IFSNNMEYDD
GDPEPVQGAF YTSSSYHKPV FNYFREEEIL NLTALLKPVS DDDELKVLKD SNLEVIRSNP
EFQINKQPER PTNRICTSLL SRERLAFILR YALAYVSESD GLQKHIMRYP QLFATKAIEQ
KLSEGVKKGI IWHTQGSGKT ALTFYNVRFL TDYFQQQHVI PKFYFIVDRL DLLQQAQREF
TARGLTVHTI NSRDAFTRDI KATQVIHNHS GKPEITVVNI QKFKDDPDVV STKDYNVAIQ
RVYFLDEVHR SYNPKGSFLA NLSQSDSNAI KIGLTGTPLL GDDYNSRALF GDYIHKYYYN
ASIADGYTLR LIREEISIQY KIELQKALEE AEVKMGDVDR KLIYAHPSFV EPMLTYIVND
FEKSRGTLND TTIGGMVICD SSEQAKQMFE IFNGVYAQHI SSPYELKDSA QALIKAAKPD
SYAAKAKQDN KVKSAALILH DIGTKEDRKN WVENFKAGKI DFLFVYNMLL TGFDAKRLKK
LYLGRVIRKH NLLQALTRVN RTYKDFRYGY VVDFADIRKE FDATNKAYFD ELQSELGDEM
EHYSHLFKSQ EEIKQEIEHI KDVLFRFDTD NMEEFCNQIS QIQDRDTVLA LKKALADARS
LYNLIRLQGE YDFLDELDFA KLNVLYRETS NHLDLLNLKN DLETGQDTSN LLNRALEDVI
FKFVKIGEEE LVLADKLKNT LRQTREALAS NFDQQDPQFI SLKEELERLF KKKNLSEVTQ
DEMVANIDAL NKIHDRVKEL NRQNNQLRQK YLGDAKYTRI HKRLQERQQS QSDISESERK
IFAALAGVKQ DADEQVLNNS QVLDNESYFE RQMMPLVIGR FKKEQQIKLN ADASRYINHL
VVAEYLKEFN TGSQAW
//
