ID A0A1T2KWB5_9GAMM Unreviewed; 591 AA.
AC A0A1T2KWB5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=NADP oxidoreductase {ECO:0000313|EMBL:OOZ37147.1};
GN ORFNames=BOW51_03830 {ECO:0000313|EMBL:OOZ37147.1};
OS Solemya velesiana gill symbiont.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; sulfur-oxidizing symbionts.
OX NCBI_TaxID=1918948 {ECO:0000313|EMBL:OOZ37147.1, ECO:0000313|Proteomes:UP000190896};
RN [1] {ECO:0000313|EMBL:OOZ37147.1, ECO:0000313|Proteomes:UP000190896}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Se-Cadez {ECO:0000313|EMBL:OOZ37147.1};
RA Russell S.L., Corbett-Detig R.B., Cavanaugh C.M.;
RT "Mixed transmission modes and dynamic genome evolution in an obligate
RT animal-bacterial symbiosis.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OOZ37147.1}.
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DR EMBL; MPRJ01000017; OOZ37147.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T2KWB5; -.
DR OrthoDB; 9805533at2; -.
DR Proteomes; UP000190896; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 1.10.10.1590; NADH-quinone oxidoreductase subunit E; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR041921; NuoE_N.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01257; 2Fe-2S_thioredx; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00644; COMPLEX1_51K_1; 1.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000190896}.
FT DOMAIN 469..514
FT /note="NADH-ubiquinone oxidoreductase 51kDa subunit iron-
FT sulphur binding"
FT /evidence="ECO:0000259|SMART:SM00928"
SQ SEQUENCE 591 AA; 65056 MW; 858EB6B08FBAE770 CRC64;
MTDDHITETT NRVMTQWNND QSNLLQMLID LQQALNGIPE SAINQISAGT RRSPADIESV
IGFYSFLHHD THNPYRVLFS DNITDRMLGS RALAEHLNSR LQDIDTATVD YTSCTGMGDQ
GPAALVNGHT LTRLDKERID QMAALMETNT PLSDWPAEWF RVDENIRRRD LLLETDFEKG
SAIKCALESG AEKILEELDA SGLRGRGGAG FKTAMKWRFC REATGDNRVV VCNADEGEPG
TFKDRLLLQS FAERLIEGMT VCAKVIGATT GFIYLRGEYL YLRDELESKL QRYRDAGLLS
KDIHGEAGFD FDIKIHLGAG AYICGEESAL IESLEGKRGI PRIRPPFPVT SGYLNRPTVV
NNVETLVAAA MIAVHGAAWF RTKGTEQSPG TKLLSISGNC LKPGIYEYPF GTSLEVILKD
CEATHVQAVQ IAGAAGSCIP PSEFSRSIAF EDLATGGSFM IFDRERNLLE MVQNFTDFFV
HESCGFCTPC RVGTSLLKKR LAKVASGRAT GVDLEKMRII GSLTRQTSHC GLGMTAANPI
LETLDKFPHI YEPHLLSTTF EPAFNLDASL EEARQITGRD DPDAHLQGGG V
//
