ID   A0A1T3NMB5_9ACTN        Unreviewed;       445 AA.
AC   A0A1T3NMB5;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=MFS transporter {ECO:0000313|EMBL:OPC77934.1};
GN   ORFNames=B4N89_37495 {ECO:0000313|EMBL:OPC77934.1};
OS   Embleya scabrispora.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Embleya.
OX   NCBI_TaxID=159449 {ECO:0000313|EMBL:OPC77934.1, ECO:0000313|Proteomes:UP000190037};
RN   [1] {ECO:0000313|EMBL:OPC77934.1, ECO:0000313|Proteomes:UP000190037}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NF3 {ECO:0000313|EMBL:OPC77934.1,
RC   ECO:0000313|Proteomes:UP000190037};
RA   Vazquez M., Ceapa C.D., Rodriguez Luna D., Sanchez Esquivel S.;
RT   "Draft genome sequence of Streptomyces scabrisporus NF3, endophyte isolated
RT   from Amphipterygium adstringens.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OPC77934.1}.
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DR   EMBL; MWQN01000003; OPC77934.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T3NMB5; -.
DR   STRING; 159449.B4N89_37495; -.
DR   OrthoDB; 5494559at2; -.
DR   Proteomes; UP000190037; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06173; MFS_MefA_like; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR010290; TM_effector.
DR   PANTHER; PTHR23513:SF9; ENTEROBACTIN EXPORTER ENTS; 1.
DR   PANTHER; PTHR23513; INTEGRAL MEMBRANE EFFLUX PROTEIN-RELATED; 1.
DR   Pfam; PF05977; MFS_3; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   4: Predicted;
KW   Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190037};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        97..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        239..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        272..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        300..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        323..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        390..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          233..445
FT                   /note="Major facilitator superfamily (MFS) profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50850"
FT   REGION          424..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        427..445
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   445 AA;  46374 MW;  BBEF9A96A4624EDF CRC64;
     MTPTPAAKAS RGIGARIRRA AVDTRPFAVP AYRRVLVGQG ASLVGTMVTE VTVPVQIYSI
     THSSFYVGLA GLFGFVPIVV FGLYGGAVAD RVDRRRLCLW SSLVTWAVTI ALFAQTLLHA
     RSEFLLLGLV AVQGAGFATA SSARGAIIPR IVPHELIPAA NTLSFTVGNI GQIAGPLVAG
     VLLTLPQGFA YAYGADAILF TLSLYSTWRL PPIPPAGAAT GTGTGGVFEG LRFIGGSPIL
     LMSFAVDIAA MVLAMPNALF PEAAATRFHG GIGVLYSAVA IGSLLAGLCS GWIARVRRQG
     VALTLAVVAW ASAITLAGFT RALWLAVALL VLAGAADLVS AVYRQTILQT WAPDEMRGRM
     QGVFTVVVAG GPRLGDLRAG AMAATTTLGI AWSGSAMLCI VLVLVGALAV RPFWHYDAHR
     RHPECPPPAP DPPIPRSQSP AEPAR
//