ID A0A1T3NSJ3_9ACTN Unreviewed; 375 AA.
AC A0A1T3NSJ3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:OPC79867.1};
GN ORFNames=B4N89_01950 {ECO:0000313|EMBL:OPC79867.1};
OS Embleya scabrispora.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Embleya.
OX NCBI_TaxID=159449 {ECO:0000313|EMBL:OPC79867.1, ECO:0000313|Proteomes:UP000190037};
RN [1] {ECO:0000313|EMBL:OPC79867.1, ECO:0000313|Proteomes:UP000190037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NF3 {ECO:0000313|EMBL:OPC79867.1,
RC ECO:0000313|Proteomes:UP000190037};
RA Vazquez M., Ceapa C.D., Rodriguez Luna D., Sanchez Esquivel S.;
RT "Draft genome sequence of Streptomyces scabrisporus NF3, endophyte isolated
RT from Amphipterygium adstringens.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPC79867.1}.
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DR EMBL; MWQN01000001; OPC79867.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T3NSJ3; -.
DR STRING; 159449.B4N89_01950; -.
DR OrthoDB; 213853at2; -.
DR Proteomes; UP000190037; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR CDD; cd06578; HemD; 1.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.10090; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR039793; UROS/Hem4.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR40082; BLR5956 PROTEIN; 1.
DR PANTHER; PTHR40082:SF1; BLR5956 PROTEIN; 1.
DR Pfam; PF02602; HEM4; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000190037}.
FT DOMAIN 278..373
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 278..373
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 375 AA; 40322 MW; F6FE2A853B60EF40 CRC64;
MVTRTGAAEP LVGLTVGVTA ARRRDELVAL LERRGAKVVG TPTMSIVPLR EDRELRRATE
RCLVEPLDYV VATTGVGWRG WMNAAEGWGR SAEVRRVCAA ATVISRGPKA TGAVRASGLR
EMYSPGSEAN DELLHWLLAR DLRGRRIAVQ EHGAPLEGFA TALRERGAEV IELPVYRWGP
PEDPAAVRRL VEQVVRGEVH AMTFTSAPAI DAFLAAAGEA GRREQVLAAL RADVLPVCIG
AICAKPLGEE GVPALWPERG RLGSMVRTVT ETLPARVRRE LDTGTDRLVL QGNAVLVRGG
VIALSPVPAA VLRALAEKPG WVLSRAELLR RVWQGASADE HAVEAAVARL RSALGPHKGL
VKTVTKRGYR LAVPV
//
