ID   A0A1T3P5I2_9ACTN        Unreviewed;       909 AA.
AC   A0A1T3P5I2;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=RNA helicase {ECO:0000313|EMBL:OPC84316.1};
GN   ORFNames=B4N89_28325 {ECO:0000313|EMBL:OPC84316.1};
OS   Embleya scabrispora.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Embleya.
OX   NCBI_TaxID=159449 {ECO:0000313|EMBL:OPC84316.1, ECO:0000313|Proteomes:UP000190037};
RN   [1] {ECO:0000313|EMBL:OPC84316.1, ECO:0000313|Proteomes:UP000190037}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NF3 {ECO:0000313|EMBL:OPC84316.1,
RC   ECO:0000313|Proteomes:UP000190037};
RA   Vazquez M., Ceapa C.D., Rodriguez Luna D., Sanchez Esquivel S.;
RT   "Draft genome sequence of Streptomyces scabrisporus NF3, endophyte isolated
RT   from Amphipterygium adstringens.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OPC84316.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MWQN01000001; OPC84316.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T3P5I2; -.
DR   STRING; 159449.B4N89_28325; -.
DR   eggNOG; COG4581; Bacteria.
DR   Proteomes; UP000190037; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:OPC84316.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190037}.
FT   DOMAIN          40..198
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          275..476
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          632..666
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        644..666
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   909 AA;  100243 MW;  3EC2E2BF792C6F96 CRC64;
     MSPAEHYAAA RRRAADERTS LHAFREQYPF GLDGFQVEAC RALEAGKGVL VAAPTGSGKT
     VVGEFAVHLA LEQGRKCFYT TPIKALSNQK FADFQKLYGA ANVGLLTGDN SVNADAPVIV
     MTTEVLRNML YASSNALAGL GYVVMDEVHY LSDRFRGAVW EEVIIHLPES VTLVSLSATV
     SNAEEFGDWL GTVRGDTEVV VSEHRPVPLW QHVIAGNRTY DLFTDENHTE VNPELVRLGR
     MESERAGRPQ DRYRRNRGQE TRPVRSRIWT PSRAEVIDRL DAEGLLPAIT FIFSRKGCEA
     AVQQCLHAGL RLNGDAERAE VRTIVEARTT GIPDEDRHVL GYHSWLDALQ RGIAAHHAGM
     LPTFKEVVEE LFVKGLVKAV FATETLALGI NMPARSVVLE KLVKWNGETH ADLTAGEYTQ
     LTGRAGRRGI DIEGHAVVLW HQGFDAAHLA GLAGTRTYPL RSSFKPSYNM AVNLVGQVGR
     HRSRELLETS FAQFQADRSV VGLTRQVQRN EEGLAGYREA MTCHLGDFAE YGSLRRALKD
     RESELAREGA VQRRAAAAAS LEKLKSGDII MVPTGKYAGL AVILDPGTDQ GPEGPRPFVL
     TVDRQVRRLA GIDFPVPVEA IDRLRIPRSF NARNPQSRRD LASSLRTKAG HVDHPRGRKQ
     RSPAADDAEL ARLRQAIRQH PCHGCDDREE HARWAERYHR LLRDTQVIES RMKGRTHTIA
     RTFDRVCAML TDLGYLAGDT VTEDGRRLAR IYAELDLLTA ECLREGLWEE LSPAELAACA
     SALVYESRQP DDAMSPKVPA GTTTSALVDM VRLWGHLDAL EGQHHLDFLR EPDLGFAWTA
     YSWASGMSLD AVLGDADLPA GDFVRWIKQL VDVLGQIAAA APDDSKVGGT ARKAIEGLRR
     GVVAYSSVG
//