ID A0A1T3P5X5_9ACTN Unreviewed; 1284 AA.
AC A0A1T3P5X5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN ORFNames=B4N89_28800 {ECO:0000313|EMBL:OPC84392.1};
OS Embleya scabrispora.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Embleya.
OX NCBI_TaxID=159449 {ECO:0000313|EMBL:OPC84392.1, ECO:0000313|Proteomes:UP000190037};
RN [1] {ECO:0000313|EMBL:OPC84392.1, ECO:0000313|Proteomes:UP000190037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NF3 {ECO:0000313|EMBL:OPC84392.1,
RC ECO:0000313|Proteomes:UP000190037};
RA Vazquez M., Ceapa C.D., Rodriguez Luna D., Sanchez Esquivel S.;
RT "Draft genome sequence of Streptomyces scabrisporus NF3, endophyte isolated
RT from Amphipterygium adstringens.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPC84392.1}.
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DR EMBL; MWQN01000001; OPC84392.1; -; Genomic_DNA.
DR STRING; 159449.B4N89_28800; -.
DR OrthoDB; 3344388at2; -.
DR Proteomes; UP000190037; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000190037};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1250..1274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 892..1057
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 280..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 958..983
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..360
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1284 AA; 136175 MW; F317233C0F29B15A CRC64;
MDATDRHDRP RETAGTLRAH WAWYHDGAVP ACSAGPERRA HFERLVRPTL DEYAPPGWVG
VTGAGREDSF VAMTLRDPEG VRYFTAPYAE IAAAGATYTA LWLAFRGIDL PTDRERPLRV
RLPGPAPTAA LHLDDFEWLA GVAAAVLAGP VVITGADRLD SRARLELLDR ITALLPYGCR
AGLRFATSLG PTGRLRPRLA FGRVPAPGTV RVALDGVPAV PDLPAARAYL GELTMLRRRI
GLDPLVAALA TLREAGPPVA GDRLLGLLAE VGARFGPGAG VGVGNGSGVR VGNGSGVRVG
PAPGSEPGRE AARFAAEDPT GPSSRARGVE ARPSPSPVHP SPPPTRPSPP PPPSPPPSPL
ERLLGGDVAL AAPIAERWRA EDGDDVTRDM AAALRARPAS LALGWNTAVA AGRGDRLVHV
LLGPVPPLLA GSTPPAGLDA RALRVPEPSV NGAGKADADV VSPEALVADL CRLLGPTPTT
EVPALYDALW NHPVVLRRLL DTAGGDLGAW LGVIRPWDDR APEWLAPYAL LAGERLRPAE
IPPAEAVFTL RVAGRTDTAT IAAVLHDLWP TLVPLTEQRA DPAARGLAAL LEKPLGPAAP
VAARVRADVL RLALGGAPTD GPYVAADLLA LRHEPVAEGR FAGWIAALLR AVAVTPELLG
ELVRAGDPAV TAAVADAVLA DARLAELPGL DDAWWAAIAR ARPELAGRAA SGWFRNALRG
ADARAAAGVW AGEIVDGAAR PRRDLYVHEV GRWWHAAPDR ERDLLLPSLE RELIVRGGTP
AQAREELRAI RVAIAAHAWG PEAASSIVER EQEEFETFRR HLKQLRAALK HGDALRVLAI
PAILALIALL AAVPPGGAAA AARPPTARTE PPDPYGAERL ITTLGADRER VNYVILVDTS
ASMRRTGRYA TARSALTAFL ARLTARDRVA LVTFDGVATE HGNGLEPVTD PAAMAARLPL
PRPSEPADAN PAGGAPPLRA EPPSDVHAAL ERALVVLRTS APDSVNGVVL ISDAARDAVG
PDLRKDFDRL GEEGRAVAGF AVPLASDSSA GPALQRVLPN TRELRDDPAD PGIALTQART
GLYLRHAARF VDADRDKGVQ ATWLMPPPEQ PDAVDCRAFR PVPPDRRLDL SSGREMCLRL
VAGTTRVPLQ VTRLRVDGVG VVGLKDGAPL LAPGQPVYFS VNLAARTHRT DGMWADAGHY
DARARVVGEV HSPLAETIKQ QLPDARLALR TDVVGDELLY RGDERVDLSW WPWLLAGLGT
LAVAGVAWFG WSWVRPRVRR RWVR
//
