ID A0A1T3P610_9ACTN Unreviewed; 329 AA.
AC A0A1T3P610;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=RNA polymerase subunit sigma-70 {ECO:0000313|EMBL:OPC84432.1};
GN ORFNames=B4N89_29035 {ECO:0000313|EMBL:OPC84432.1};
OS Embleya scabrispora.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Embleya.
OX NCBI_TaxID=159449 {ECO:0000313|EMBL:OPC84432.1, ECO:0000313|Proteomes:UP000190037};
RN [1] {ECO:0000313|EMBL:OPC84432.1, ECO:0000313|Proteomes:UP000190037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NF3 {ECO:0000313|EMBL:OPC84432.1,
RC ECO:0000313|Proteomes:UP000190037};
RA Vazquez M., Ceapa C.D., Rodriguez Luna D., Sanchez Esquivel S.;
RT "Draft genome sequence of Streptomyces scabrisporus NF3, endophyte isolated
RT from Amphipterygium adstringens.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Interacts transiently with the RNA polymerase catalytic core
CC formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1
CC omega subunit) to form the RNA polymerase holoenzyme that can initiate
CC transcription. {ECO:0000256|ARBA:ARBA00011344}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC {ECO:0000256|ARBA:ARBA00010641}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPC84432.1}.
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DR EMBL; MWQN01000001; OPC84432.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T3P610; -.
DR STRING; 159449.B4N89_29035; -.
DR eggNOG; COG1595; Bacteria.
DR OrthoDB; 7376212at2; -.
DR Proteomes; UP000190037; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR Gene3D; 1.10.1740.10; -; 1.
DR Gene3D; 3.10.450.50; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR039425; RNA_pol_sigma-70-like.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR014305; RNA_pol_sigma-G_actinobac.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR037401; SnoaL-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR NCBIfam; TIGR02960; SigX5; 1.
DR PANTHER; PTHR43133:SF46; ECF RNA POLYMERASE SIGMA FACTOR SIGG; 1.
DR PANTHER; PTHR43133; RNA POLYMERASE ECF-TYPE SIGMA FACTO; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF08281; Sigma70_r4_2; 1.
DR Pfam; PF12680; SnoaL_2; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000190037};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 21..83
FT /note="RNA polymerase sigma-70 region 2"
FT /evidence="ECO:0000259|Pfam:PF04542"
FT DOMAIN 137..189
FT /note="RNA polymerase sigma factor 70 region 4 type 2"
FT /evidence="ECO:0000259|Pfam:PF08281"
FT DOMAIN 212..306
FT /note="SnoaL-like"
FT /evidence="ECO:0000259|Pfam:PF12680"
SQ SEQUENCE 329 AA; 36113 MW; B9AF6E7A7F1E1A72 CRC64;
MSDLVATDGA DVVEEQFEPF RVELTGYCYR MLGSVFEAED AVQDTMVRAW KSFDRFEGRS
SVRSWLYRIA TNVCLDSLNG RERRARPMDL SSPVPASSAL TPARPEATWI EPIPDGRVVP
SVADPAEVAV ARESVRLAFV AALQHLPPRQ RAVLILREVL AWKASEVAEL LGSSVASVNS
ALQRARAALA EGEITATDPV RPMDEEQQSL LARYVDAFER YDLDSLTALL REDATLSMPP
YELWLRGHAD IREWFLGTGI GCRGSRLVPI VANGTPGFGQ YRSSGPGGSF EPWALQVIEI
SEGQIIGLNA FLDVPHLFPL FGLPATLDA
//
