ID A0A1T4PD00_VIBCI Unreviewed; 462 AA.
AC A0A1T4PD00;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN02745782_01663 {ECO:0000313|EMBL:SJZ89197.1};
OS Vibrio cincinnatiensis DSM 19608.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=1123491 {ECO:0000313|EMBL:SJZ89197.1, ECO:0000313|Proteomes:UP000190834};
RN [1] {ECO:0000313|EMBL:SJZ89197.1, ECO:0000313|Proteomes:UP000190834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19608 {ECO:0000313|EMBL:SJZ89197.1,
RC ECO:0000313|Proteomes:UP000190834};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FUXB01000007; SJZ89197.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T4PD00; -.
DR STRING; 1123491.SAMN02745782_01663; -.
DR OrthoDB; 9804645at2; -.
DR Proteomes; UP000190834; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.170; Two-component histidine kinase, sensor domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR031930; HK_sensor.
DR InterPro; IPR038428; HK_sensor_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR45436:SF5; SENSOR HISTIDINE KINASE TRCS; 1.
DR PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF16750; HK_sensor; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SJZ89197.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 181..236
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 244..456
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 217..248
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 462 AA; 52766 MW; 4DBA8B28320E2A0E CRC64;
MLNRITAFFR QCIALQKRLV IRLFASLALS VLLVLTAFTA VEMLLLDHFL TLPKALQTEL
RLLAEQAKQQ LAHEDRQALA QWERSAPYLV HVVNDRLQPL SERNIHPHVL QKMRYSRQWD
EPMGAKVSKP MIRLPLTDHE LLMVQLPWQQ HPASRAGYYL WFANLIVTMP ILALMSWILS
RQLQRPLTRL QSASRALALG ETEARVANTL GRTAQEFQEL ATDFDQMAEQ IQQLVDEQRK
LVRTLSHELK TPLTRQSLAL HLAQQANNEE DRHEWLDRAG QEAELMDSMI EKILALSRLE
GCRLPVTLIP MDVNAYLTEQ VEQFRPHLKP QQQLHFFASM ESGWILADRV LLGSAVNNVL
TNAVKYAGER GVINMRVDVR PTQLLISVAD NGQGVSDDDL EHLFKPFYQV KKTPTQCSGY
GLGLSIVKQS VHKMNGRVCA KNEQGLVIDF TFPRYDGLNK VP
//
