ID   A0A1T4PTM7_9FIRM        Unreviewed;       420 AA.
AC   A0A1T4PTM7;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=GHKL domain-containing protein {ECO:0000313|EMBL:SJZ94915.1};
GN   ORFNames=SAMN02745110_02121 {ECO:0000313|EMBL:SJZ94915.1};
OS   Eubacterium ruminantium.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Eubacterium.
OX   NCBI_TaxID=42322 {ECO:0000313|EMBL:SJZ94915.1, ECO:0000313|Proteomes:UP000189857};
RN   [1] {ECO:0000313|EMBL:SJZ94915.1, ECO:0000313|Proteomes:UP000189857}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17233 {ECO:0000313|EMBL:SJZ94915.1,
RC   ECO:0000313|Proteomes:UP000189857};
RA   Peterson S.W.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FUXA01000014; SJZ94915.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T4PTM7; -.
DR   OrthoDB; 9813149at2; -.
DR   Proteomes; UP000189857; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   Gene3D; 1.10.287.130; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR032834; NatK_C.
DR   InterPro; IPR016120; Sig_transdc_His_kin_SpoOB.
DR   Pfam; PF14501; HATPase_c_5; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55890; Sporulation response regulatory protein Spo0B; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189857};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        33..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        57..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        82..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        119..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        148..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        182..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          321..418
FT                   /note="Sensor histidine kinase NatK C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14501"
SQ   SEQUENCE   420 AA;  48021 MW;  07ABFC8A78797C2F CRC64;
     MKMEIIYLWS FLEALKIYLM FRYILGFEIN KKIYIWFVLM YPIIVLPVVA VCDSNRLFIY
     KAVWLFAFPI IFFKGKTSLK AVLTFAVSTL ISLIDIVILN LLSYIKVKKP ANYDWRNDMS
     VILILLSAIL CFRYKNKVNK AISSLNPGIK FGILIISFVL YLWVGVLQLI FTAGPESRIS
     GYASFISIIV AGVLLFLLMV GIYHITRISQ ILAVDEYKSR MLDISRQYVD SLVEREKDLR
     SYKHDFNNHL MMIKSMASDN SDQEVVRYID DIFGKYKIKN VITTGNRIAD VFINKVIGEM
     ADDDGFLSQV IGEFPKDMKI DSVDMSTLMS NIMDNALEAM QRISGTKKLL IEIKHFENML
     YLDVANSAAV EDKDLISKKK EAGHGFGAGK IKDVVLKNGG AVNWEYKNGM MEVRVELPVR
//