ID A0A1T4PXH1_9BACT Unreviewed; 970 AA.
AC A0A1T4PXH1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=TOMM system kinase/cyclase fusion protein {ECO:0000313|EMBL:SJZ96203.1};
GN ORFNames=SAMN04488128_10251 {ECO:0000313|EMBL:SJZ96203.1};
OS Chitinophaga eiseniae.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Chitinophaga.
OX NCBI_TaxID=634771 {ECO:0000313|EMBL:SJZ96203.1, ECO:0000313|Proteomes:UP000190367};
RN [1] {ECO:0000313|EMBL:SJZ96203.1, ECO:0000313|Proteomes:UP000190367}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22224 {ECO:0000313|EMBL:SJZ96203.1,
RC ECO:0000313|Proteomes:UP000190367};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FUWZ01000002; SJZ96203.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T4PXH1; -.
DR STRING; 634771.SAMN04488128_10251; -.
DR OrthoDB; 9813021at2; -.
DR Proteomes; UP000190367; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:SJZ96203.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000313|EMBL:SJZ96203.1}.
FT DOMAIN 15..272
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 970 AA; 108268 MW; 9B47321E980150F1 CRC64;
MKPSKHGPFP SMEYYSIVET LFESMHSCVY KAIRKNTRQY VAIKLIKGNS LSDRQRQERF
EREVRICSEI NHPCIVKLLD TGYTGDHIPF VVFEYIAGIT LKQFIQQHGV IHLPLAAELM
GQVLDALACA HSMGIVHRDL KPENIMITQP GARPYAKVLD FGISIFTGDG FPADDTAGTP
AYCAPEQLRG EPPSVRSDLY AWGLVLTECI TGTPVISGGT LTAVYEQQLS ADPVPLPGFL
TEHPLGNLLQ RVLEKKAVDR AADAHLLLQE LAATELTVPP MAAVTHTMRK FSSMETMDNM
LSWHYEKREK RLVTVLCIKL ETVACKGLQP EEDVLEELLH RQLRGCAAIA ARFGGFVKGM
MAGNLLIYFG YPQATDNDAR MACRTALEVL GEMQQHNLLL HEQQRITLVT RQTIHTGIII
SRENRVAEGT TPGTGFNLLQ DTPADRILVT GTTAALISHF AELEKCHHLP GEGCVGVRET
FYVLKERRAE VFSRLYATAA NRSMHGRAEA LDTIIRCYER VEETHREVVL ITGEAGIGKS
RLMLEARKKM TGVMLIERRC LPEHKHRTLF PFIEIIRQYY GLYQQAGGRA VSLLEQLLSA
AGCDLAVTMP VVLACFGWPF TDCYPPSQAA PADQKRLLFQ ALKKCMINIS RKKKYVLLLE
DLHWMDPGSH EFLADMMADR GQGGCMFLLS ARTNFTPSWH TTLFTRLPLE PLDEPAVKAM
VEEQLGHGKK IAPAALHYIL QHTGGVPFFV EELLQLLLAE GWLTSAEHIY HLIRENRLPG
VPLTLKELLQ AKLDQAGAAK ETAQLAATIG REFSSRLLIK VAMKEAGSVW KDLQVLTAAD
ILIPLRTEKG LYYVFRHMLF CEVTYDSQSP PARKQAHARI AEALMASVPP DEQPDVLLMN
ELAQHLHGAG NVAAAIEWQL TGIQQLISTS ANRECISLCE QALQWLRELP ADQVALRISR
KSYETVLSAR
//
