ID A0A1T4Q8F6_9GAMM Unreviewed; 628 AA.
AC A0A1T4Q8F6;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Protease-4 {ECO:0000313|EMBL:SJZ99916.1};
GN ORFNames=SAMN02745674_01543 {ECO:0000313|EMBL:SJZ99916.1};
OS Lysobacter spongiicola DSM 21749.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Lysobacter.
OX NCBI_TaxID=1122188 {ECO:0000313|EMBL:SJZ99916.1, ECO:0000313|Proteomes:UP000190061};
RN [1] {ECO:0000313|EMBL:SJZ99916.1, ECO:0000313|Proteomes:UP000190061}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21749 {ECO:0000313|EMBL:SJZ99916.1,
RC ECO:0000313|Proteomes:UP000190061};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S49 family.
CC {ECO:0000256|ARBA:ARBA00008683}.
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DR EMBL; FUXP01000004; SJZ99916.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T4Q8F6; -.
DR STRING; 1122188.SAMN02745674_01543; -.
DR OrthoDB; 9764363at2; -.
DR Proteomes; UP000190061; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR CDD; cd07018; S49_SppA_67K_type; 1.
DR CDD; cd07023; S49_Sppa_N_C; 1.
DR Gene3D; 6.20.330.10; -; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR004634; Pept_S49_pIV.
DR InterPro; IPR004635; Pept_S49_SppA.
DR InterPro; IPR002142; Peptidase_S49.
DR InterPro; IPR047217; S49_SppA_67K_type_N.
DR InterPro; IPR047272; S49_SppA_C.
DR NCBIfam; TIGR00705; SppA_67K; 1.
DR NCBIfam; TIGR00706; SppA_dom; 1.
DR PANTHER; PTHR33209; PROTEASE 4; 1.
DR PANTHER; PTHR33209:SF1; SERINE PROTEASE SPPA, CHLOROPLASTIC; 1.
DR Pfam; PF01343; Peptidase_S49; 2.
DR PIRSF; PIRSF001217; Protease_4_SppA; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:SJZ99916.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000190061};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825}.
FT DOMAIN 137..294
FT /note="Peptidase S49"
FT /evidence="ECO:0000259|Pfam:PF01343"
FT DOMAIN 396..547
FT /note="Peptidase S49"
FT /evidence="ECO:0000259|Pfam:PF01343"
FT ACT_SITE 206
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001217-1"
FT ACT_SITE 413
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR001217-1"
SQ SEQUENCE 628 AA; 68006 MW; CC2E94CF4C17A6C0 CRC64;
MNQPSRRGPI ARFFIGLWDA MNFTRRLIFN LIFFFLLFAI LAALSAGDRT QPLLDRTTLV
IEPEGMLVEQ YTVDPATRAI TRAMGEEATE VQLRDLLRTL DEAREDDRIE RVVLQLDGLY
GGGMASRREV AAAVARLRES GKQVIAFSEA MGQEQYLIAA QANEIYLDPM GGLMLEGLGR
YRQYYREGLE EKLGVDVHLF KVGEYKSAAE PFILDQASEE SKEADLYWMN DLWGRYLADV
GTARGIAPAS IAADIEQLPQ DVAAVQGDLA RYALEHKLVD GLKTREQLDD LLAERGEADA
DAEGGFRQVS MEGYLGHLVK PLNAAADPRP HVAVVVAAGG ITGGEQPPGT IGGESTSALL
RQARDDDRAK AVVLRVNSPG GEVFASEQIR REVVALQQAG KPVVVSMGDL AASGGYWISM
DADRIYADPS TITGSIGIFG MIPTIPRALD KMGINTDGVG TTRFAGAFNI TRELDPGVGE
VIQSVIEKGY RDFIGKVAEA REMPVAGVDE VARGRVWSGA QAMDRGLVDE LGGLQQAIVD
AAARAELGEP GDYPVHYVEK PATPFEQFFT GFAQTRIGSA LLRDSSLARS VLASALPQAE
ADLKLLEGTF KQTAGVPVKS LAYCFCTL
//
