ID A0A1T4R441_9GAMM Unreviewed; 632 AA.
AC A0A1T4R441;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN ORFNames=SAMN02745674_01954 {ECO:0000313|EMBL:SKA10832.1};
OS Lysobacter spongiicola DSM 21749.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Lysobacter.
OX NCBI_TaxID=1122188 {ECO:0000313|EMBL:SKA10832.1, ECO:0000313|Proteomes:UP000190061};
RN [1] {ECO:0000313|EMBL:SKA10832.1, ECO:0000313|Proteomes:UP000190061}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21749 {ECO:0000313|EMBL:SKA10832.1,
RC ECO:0000313|Proteomes:UP000190061};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FUXP01000007; SKA10832.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T4R441; -.
DR STRING; 1122188.SAMN02745674_01954; -.
DR OrthoDB; 9803824at2; -.
DR Proteomes; UP000190061; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 2.60.40.2380; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF07696; 7TMR-DISMED2; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000190061};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..632
FT /note="diguanylate cyclase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013024319"
FT TRANSMEM 209..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 485..620
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT COILED 412..443
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 632 AA; 69475 MW; 588F0CC1AC300CD1 CRC64;
MRRFGAAARF WILLVASAWL TPSVVAVAVP LQAATHQVAP PVTVELQPDT GSVGLSPYVS
FHHDPDGELR VAGARRLAAS GGFEPLPQGN PAFGFQPGAF WFHVRVVNHD PGEQKRFLVQ
DYPLSDRLDL YVVGADGQVR HAAGGDNLPF ARRAVEYHMP SFELLLPAGE PVDLLLRVRS
QSSMQVPLVL HTPASLAEAM HDAQWGIGLY YGILLALFVY NLVLWLMLRD ASYLWYLLHI
IAFGLVLFTL NGLGFQYLWP DSPWFADRAV PLSICLAQVG MQQFARHFLE LHERWRFGDR
VGLAMIGFFV LLAIASLQLP YRISTPLASA AVFVSIAWIA IESIVVMSRG YKPARLFLLA
WSMFLLGTAM IAAVAFGLLP KTFVTIYGVQ IGSALEMLLL SVALGYRYAA LRNENERIVH
RAKAELERQV EERTTELRNA LAQLGDAHAR LRESSRRDGL TGLHTRAHFR EGFGQLIARA
RANGRPLSLL MIDLDHFKQI NDCHGHLVGD DCLRWAAHVV GQALRPHEAL LARFGGEEFV
VGLPDLGRTA ATAVAAELVR QLRASPCESG GRSIAVTASI GVHELDLLGG EDTDAALQCA
DEALYQAKAD GRDCVRWLPE DAVPPPRTLA LG
//
