ID A0A1T4RA91_9BACT Unreviewed; 616 AA.
AC A0A1T4RA91;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Chloride channel protein, CIC family {ECO:0000313|EMBL:SKA12847.1};
GN ORFNames=SAMN04488128_102976 {ECO:0000313|EMBL:SKA12847.1};
OS Chitinophaga eiseniae.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Chitinophaga.
OX NCBI_TaxID=634771 {ECO:0000313|EMBL:SKA12847.1, ECO:0000313|Proteomes:UP000190367};
RN [1] {ECO:0000313|EMBL:SKA12847.1, ECO:0000313|Proteomes:UP000190367}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22224 {ECO:0000313|EMBL:SKA12847.1,
RC ECO:0000313|Proteomes:UP000190367};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FUWZ01000002; SKA12847.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T4RA91; -.
DR STRING; 634771.SAMN04488128_102976; -.
DR OrthoDB; 9812438at2; -.
DR Proteomes; UP000190367; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 2.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 47..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 492..550
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 557..615
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 616 AA; 68234 MW; 296947C051152AEC CRC64;
MSRFSRIRKH HSFFRFKREF EEYSLRKAKS YELVLHWLHT KLNRNQFLLL SGILVGCSAG
LAGVALKMLV HYIHYIITYK VHFSTQIIFY IVFPFLGIVL TTLIVIFFFK GQSRKGIPAI
LHEIAQNSSI IPQVKMYSQI LQSAVTVGLG GSAGLESPIA VTGAALGSNY ARTYSLGYKE
RTLLLAAGAT AGIASAFNAP IAGMMFAFEI LLTGVVFSDF MPLVVAAVCG SLLSKIILQE
EVLFHFESRI PFNYHNVPFY IVLGLLSGFY ARYFVVLSHK VEHFFQHLQW SALRRAMLGG
VLVSALCVAL PPLFGEGYTA VKALAGGHGE VILQNSFFGY FPPQSWMLLV FTGCVCLLKA
FATSITIQSG GNGGNFAPSL FAGGFLGFFF ALLCTQIGLT DVPATNLVIV GMAGVMAGVM
YAPLTAIFLI AESSSGYDLF IPLMIVSTTS YLMAKWFSPI SPELTELAKE GKVFTKAHDN
NILLMLRMQD LVEQDIQRIN IDSDLRELIE LVKGGHRNII AVVNQQDKLE GIITLDDIRP
IMFNPELYDI VTVKKLMKAP PAVVSLKDSI TLVLKKFDEA HVWNLPVVQD KKLIGFVSKS
RILNKYRLLL QEYSEG
//
