ID A0A1T4RGY9_9BACT Unreviewed; 441 AA.
AC A0A1T4RGY9;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=inositol-3-phosphate synthase {ECO:0000256|ARBA:ARBA00012125};
DE EC=5.5.1.4 {ECO:0000256|ARBA:ARBA00012125};
GN ORFNames=SAMN04488132_11267 {ECO:0000313|EMBL:SKA15245.1};
OS Sediminibacterium ginsengisoli.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Sediminibacterium.
OX NCBI_TaxID=413434 {ECO:0000313|EMBL:SKA15245.1, ECO:0000313|Proteomes:UP000190888};
RN [1] {ECO:0000313|EMBL:SKA15245.1, ECO:0000313|Proteomes:UP000190888}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22335 {ECO:0000313|EMBL:SKA15245.1,
RC ECO:0000313|Proteomes:UP000190888};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
CC -!- PATHWAY: Polyol metabolism; myo-inositol biosynthesis; myo-inositol
CC from D-glucose 6-phosphate: step 1/2. {ECO:0000256|ARBA:ARBA00005117}.
CC -!- SIMILARITY: Belongs to the myo-inositol 1-phosphate synthase family.
CC {ECO:0000256|ARBA:ARBA00010813}.
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DR EMBL; FUWH01000012; SKA15245.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T4RGY9; -.
DR STRING; 413434.SAMN04488132_11267; -.
DR OrthoDB; 729130at2; -.
DR Proteomes; UP000190888; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004512; F:inositol-3-phosphate synthase activity; IEA:InterPro.
DR GO; GO:0006021; P:inositol biosynthetic process; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002587; Myo-inos-1-P_Synthase.
DR InterPro; IPR013021; Myo-inos-1-P_Synthase_GAPDH.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR11510:SF5; INOSITOL-3-PHOSPHATE SYNTHASE 1; 1.
DR PANTHER; PTHR11510; MYO-INOSITOL-1 PHOSPHATE SYNTHASE; 1.
DR Pfam; PF01658; Inos-1-P_synth; 1.
DR Pfam; PF07994; NAD_binding_5; 1.
DR PIRSF; PIRSF015578; Myoinos-ppht_syn; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|SAM:Phobius}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000190888};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 246..358
FT /note="Myo-inositol-1-phosphate synthase GAPDH-like"
FT /evidence="ECO:0000259|Pfam:PF01658"
SQ SEQUENCE 441 AA; 48717 MW; FDEC6689169AFCE2 CRC64;
MKEQVQSADG KLGILLPGMG AVATTVIAGV AAVNKGIAQP IGALTQMGNI RLGKRTENRY
PLIKEFVPLA ELNNVAFGGW DVYEDNVYDA AMKAKVLEPS LLNAIRPELE AIVPMKAVFD
KSFIKNLDGQ NVKEAATKME LAKEVINDIE NFKEANGCNR IVMVWCGSTE KYIETSAVHE
TLASFEAGLE NNDPAISPSM IYAYAALKLG VPFANGAPNL TCDIPALIEL AKETGTPIAG
KDFKTGQTLM KTILAPGLHA RALGVRGWFS TNILGNRDGL VLDDPDNFKT KEVSKLSVLE
DILQPDINPE LYGDLYHKVR INYYPPHGDN KESWDNIDIF GWLGYSMQIK INFLCRDSIL
AAPIVLDLAL FMDLAKRAEM SGIQEWLSFY FKSPQTAPGL RPEHDIFKQL IKLQNTLRHM
MGEDLITHLG LDYYQDLVEA L
//
