ID A0A1T4RTQ9_9GAMM Unreviewed; 451 AA.
AC A0A1T4RTQ9;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Zinc metalloprotease {ECO:0000256|RuleBase:RU362031};
DE EC=3.4.24.- {ECO:0000256|RuleBase:RU362031};
GN ORFNames=BTE48_13285 {ECO:0000313|EMBL:OPX54641.1};
OS Oceanospirillum multiglobuliferum.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Oceanospirillum.
OX NCBI_TaxID=64969 {ECO:0000313|EMBL:OPX54641.1, ECO:0000313|Proteomes:UP000191418};
RN [1] {ECO:0000313|EMBL:OPX54641.1, ECO:0000313|Proteomes:UP000191418}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33336 {ECO:0000313|EMBL:OPX54641.1,
RC ECO:0000313|Proteomes:UP000191418};
RA Carney J.G., Trachtenberg A.M., Rheaume B.A., Linnane J.D., Pitts N.L.,
RA Mykles D.L., Maclea K.S.;
RT "Genome Sequencing of a Marine Spirillum, Oceanospirillum multiglobuliferum
RT ATCC 33336, from Japan.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU362031};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase M50B family.
CC {ECO:0000256|ARBA:ARBA00007931, ECO:0000256|RuleBase:RU362031}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OPX54641.1}.
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DR EMBL; MTSM01000021; OPX54641.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T4RTQ9; -.
DR STRING; 64969.SAMN02745127_02561; -.
DR OrthoDB; 9782003at2; -.
DR Proteomes; UP000191418; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00989; PDZ_metalloprotease; 2.
DR CDD; cd06163; S2P-M50_PDZ_RseP-like; 2.
DR Gene3D; 2.30.42.10; -; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR004387; Pept_M50_Zn.
DR InterPro; IPR008915; Peptidase_M50.
DR NCBIfam; TIGR00054; RIP metalloprotease RseP; 1.
DR PANTHER; PTHR42837:SF2; MEMBRANE METALLOPROTEASE ARASP2, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR42837; REGULATOR OF SIGMA-E PROTEASE RSEP; 1.
DR Pfam; PF17820; PDZ_6; 2.
DR Pfam; PF02163; Peptidase_M50; 1.
DR SMART; SM00228; PDZ; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU362031};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362031};
KW Metal-binding {ECO:0000256|RuleBase:RU362031};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000256|RuleBase:RU362031};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:OPX54641.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000191418};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362031};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362031};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU362031}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 97..118
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 380..402
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 427..445
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT DOMAIN 194..291
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
SQ SEQUENCE 451 AA; 48990 MW; 6C21A549FA008C43 CRC64;
MSFLHTVLSL IVTLGILVTV HEFGHFWVAR RCGVKVLRFS VGFGKPLFRW RDKHNTEYAI
AWIPLGGYVS MLDEREAVVA EHERSLAFNR QSVWKRIAIV AAGPIANFIL AVITYWLVFV
SGSSALAPVI GAVTPNSLAE QAGLQANYEI VAIEGEPVRS WQEVALALLA KAGDSGEITL
QSREWQGYNE VQHFVTLDRW LAGQSTPDPL KSLGITPFSP AFPAVVGQVI EGGAAKAAGL
LVDDQILSVD AVAIQDWMQW VAVIQSSAQK TLSVEVQRAG ELVTLRLTPN SKNLSDGRAI
GYIGAAPQSV SWPEGMIREV QYGMFESIGQ AAIKTFDMTL LTLDSIRKMV VGLISVENLS
GPITIAKVAS DSAKGGLESF LTFLAYISIS LGVLNLLPIP VLDGGHLLFY FIEAVTGRPV
PEKAQQLGLR IGMMLLGSLM LIAFYNDLMR L
//
