ID A0A1T4SX93_9ACTN Unreviewed; 646 AA.
AC A0A1T4SX93;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Succinate dehydrogenase subunit A {ECO:0000313|EMBL:SKA32875.1};
GN ORFNames=SAMN02745673_04094 {ECO:0000313|EMBL:SKA32875.1};
OS Marinactinospora thermotolerans DSM 45154.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Marinactinospora.
OX NCBI_TaxID=1122192 {ECO:0000313|EMBL:SKA32875.1, ECO:0000313|Proteomes:UP000190637};
RN [1] {ECO:0000313|EMBL:SKA32875.1, ECO:0000313|Proteomes:UP000190637}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45154 {ECO:0000313|EMBL:SKA32875.1,
RC ECO:0000313|Proteomes:UP000190637};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FUWS01000012; SKA32875.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T4SX93; -.
DR STRING; 1122192.SAMN02745673_04094; -.
DR OrthoDB; 9805351at2; -.
DR Proteomes; UP000190637; Unassembled WGS sequence.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR011280; Succ_DH/Fum_Rdt_flav_su.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01811; sdhA_Bsu; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF53; SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000190637}.
FT DOMAIN 45..450
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 511..645
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 339
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630664-50"
SQ SEQUENCE 646 AA; 72204 MW; BD0CB8680D728BE9 CRC64;
MTELYIEGDP IRDEKAPEGP IEQRWDKRRF SAKLVNPANR RKLSVIIVGT GLAGASAAAT
LGEAGYQVSS FCYQDSPRRA HSIAAQGGIN AAKNYRNDGD SIYRLFYDTV KGGDFRSRES
NVYRLAQVSV EIIDQCVAQG VPFAREYGGL LDNRSFGGVQ VSRTFYARGQ TGQQLLIGAY
QALERQVAAG TVKMHTRHEM LELIVVDGRA RGIIARDMVT GEIETHFADA VVLASGGYGN
VFFLSTNAMG CNVTATWRAH RKGALFANPC FTQIHPTCIP VSGDYQSKLT LMSESLRNDG
RIWVPKKAGD QRDPRQIPED ERDYYLERIY PSFGNLVPRD IASRAAKNVC DEGRGVGPGG
LGVYLDFADA IKRMGRPAVE AKYGNLFDMY QRITGENPYE VPMRIYPAVH YTMGGLWVDY
DLQSTIPGLF VTGEANFSDH GANRLGASAL MQGLADGYFV LPNTINDYLA SGPFEKLDEN
TPEAKEAAES VRARINKLLS IDGNRTVDSF HRELGHIMWE YCGMERTEEG LRKAIERIRE
LRDEFWQNVK VVGTNDELNQ SLEKAGRVAD FFELAELMCI DALHRRESCG GHFRAESQTE
DGEALRHDDE FAYVAAWEFT GTGEQPVLHK ENLEYEYVEM KQRSYK
//
