ID   A0A1T4T1Q6_9ACTN        Unreviewed;       342 AA.
AC   A0A1T4T1Q6;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Adenosine deaminase {ECO:0000313|EMBL:SKA34440.1};
GN   ORFNames=SAMN02745673_04296 {ECO:0000313|EMBL:SKA34440.1};
OS   Marinactinospora thermotolerans DSM 45154.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Nocardiopsaceae; Marinactinospora.
OX   NCBI_TaxID=1122192 {ECO:0000313|EMBL:SKA34440.1, ECO:0000313|Proteomes:UP000190637};
RN   [1] {ECO:0000313|EMBL:SKA34440.1, ECO:0000313|Proteomes:UP000190637}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45154 {ECO:0000313|EMBL:SKA34440.1,
RC   ECO:0000313|Proteomes:UP000190637};
RA   Peterson S.W.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
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DR   EMBL; FUWS01000013; SKA34440.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T4T1Q6; -.
DR   STRING; 1122192.SAMN02745673_04296; -.
DR   OrthoDB; 105475at2; -.
DR   Proteomes; UP000190637; Unassembled WGS sequence.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   NCBIfam; TIGR01430; aden_deam; 1.
DR   PANTHER; PTHR43114; ADENINE DEAMINASE; 1.
DR   PANTHER; PTHR43114:SF6; ADENINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000190637}.
FT   DOMAIN          19..337
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   342 AA;  37489 MW;  2CB26C3C5AFF72A8 CRC64;
     MTAAAEIPSS VEAFIRDLPK VELHVHLEGS MQPATLLELA RKHGVDDLPD TIEAIADYYE
     FRDFPHFIDV YINSVRTLRD ESDFALLTRD VARRLAAQNV RYAEVHLSLY NHLLRGVPAQ
     VVFAGVEHGR IEAEREHGIR LRWIPDFPGD YGVEAGERTL EAVLAHGPAS VVGLGIGGIE
     VDRDPFADVY ARARANGLHS LPHAGENGGP GRVWSAIRVL GAERIGHGID SMKDPELVAY
     LRETQLPLDV SPTSNLRTRA VEAIGDHPLP RMVEEGLMVT LNSDDPPMFG TDLTNEYRTA
     YRIGLGLDDL AGLARNGVTA SFLDDAAKRE LTAEIDALVA RS
//