ID   A0A1T4TUQ6_9BACT        Unreviewed;       488 AA.
AC   A0A1T4TUQ6;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=adenosine deaminase {ECO:0000256|ARBA:ARBA00012784};
DE            EC=3.5.4.4 {ECO:0000256|ARBA:ARBA00012784};
GN   ORFNames=SAMN04488128_106353 {ECO:0000313|EMBL:SKA44215.1};
OS   Chitinophaga eiseniae.
OC   Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC   Chitinophaga.
OX   NCBI_TaxID=634771 {ECO:0000313|EMBL:SKA44215.1, ECO:0000313|Proteomes:UP000190367};
RN   [1] {ECO:0000313|EMBL:SKA44215.1, ECO:0000313|Proteomes:UP000190367}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22224 {ECO:0000313|EMBL:SKA44215.1,
RC   ECO:0000313|Proteomes:UP000190367};
RA   Peterson S.W.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
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DR   EMBL; FUWZ01000006; SKA44215.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T4TUQ6; -.
DR   STRING; 634771.SAMN04488128_106353; -.
DR   OrthoDB; 105475at2; -.
DR   Proteomes; UP000190367; Unassembled WGS sequence.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:UniProt.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF43; ADENOSINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
FT   DOMAIN          275..460
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   488 AA;  55681 MW;  40230653B3CDC0FB CRC64;
     MKRKMLQNVA VAAGVAGLMA LTTIPEDQDI SRQVGDYFEE VRRDPLLLTT FFTAMPKGGD
     LHHHFSGSMY GETYWQILSD HDGWINTSTV DVDTPGVAHT LPWKRFTALP RDARFDSLKQ
     AFLRTVSAKD YEVSLRPSDE HFFGTFGKMS FIASFGMEQG LRELRQRAVS ENVQYIETQT
     GQPDMRINLP ENEGWEKSLE GVSLKDSLAV FGILDKLRDS LLAHGATHWA DSCRRRMAEV
     HRNANVDDST FMVRYQLSAS RAGAPLSVYR RLLLAFEIAD RDSLVVGVNL VSREDGEVSM
     RDYQLHMLMF AHLDRSYYRR VPYSLHAGEL TAGMVRPEQL RTHITEAVMV AGARRIGHGV
     DIAYESAWKP LLDLMARKKI AIEINLSSNE FILKVKNEQH PVLLYFTRKV PVVISTDDAG
     VLRTDLTRQY VLLATRYPSL HYADIKQMVR NSIRYSFIKP AVVKEQKLRE LDAAFARFEQ
     QVLRHRAR
//