ID   A0A1T4V7V6_9FIRM        Unreviewed;       291 AA.
AC   A0A1T4V7V6;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=UDP-glucose 4-epimerase {ECO:0000256|ARBA:ARBA00018569};
DE            EC=5.1.3.2 {ECO:0000256|ARBA:ARBA00013189};
DE   AltName: Full=Galactowaldenase {ECO:0000256|ARBA:ARBA00033067};
DE   AltName: Full=UDP-galactose 4-epimerase {ECO:0000256|ARBA:ARBA00031367};
GN   ORFNames=SAMN02745111_00366 {ECO:0000313|EMBL:SKA61068.1};
OS   Eubacterium uniforme.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Eubacterium.
OX   NCBI_TaxID=39495 {ECO:0000313|EMBL:SKA61068.1, ECO:0000313|Proteomes:UP000190814};
RN   [1] {ECO:0000313|EMBL:SKA61068.1, ECO:0000313|Proteomes:UP000190814}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35992 {ECO:0000313|EMBL:SKA61068.1,
RC   ECO:0000313|Proteomes:UP000190814};
RA   Peterson S.W.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=UDP-alpha-D-glucose = UDP-alpha-D-galactose;
CC         Xref=Rhea:RHEA:22168, ChEBI:CHEBI:58885, ChEBI:CHEBI:66914;
CC         EC=5.1.3.2; Evidence={ECO:0000256|ARBA:ARBA00000083};
CC   -!- COFACTOR:
CC       Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC         Evidence={ECO:0000256|ARBA:ARBA00001911};
CC   -!- PATHWAY: Carbohydrate metabolism; galactose metabolism.
CC       {ECO:0000256|ARBA:ARBA00004947}.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. {ECO:0000256|ARBA:ARBA00007637}.
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DR   EMBL; FUXZ01000003; SKA61068.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T4V7V6; -.
DR   STRING; 39495.SAMN02745111_00366; -.
DR   OrthoDB; 9809586at2; -.
DR   Proteomes; UP000190814; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43725; UDP-GLUCOSE 4-EPIMERASE; 1.
DR   PANTHER; PTHR43725:SF51; UDP-GLUCOSE 4-EPIMERASE; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023144};
KW   Galactose metabolism {ECO:0000256|ARBA:ARBA00023144};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190814}.
FT   DOMAIN          3..204
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   291 AA;  33630 MW;  848AACF2081C0C40 CRC64;
     MNILVIGGTR FFGIPMVDDL LKKGHEVTIA TRGMAKDKYG DKVNRIIFDR CNADSIKTQL
     SNKHFDVVID KIAYCSNDVK NLLDVIDCDK YIYMSTTAVY DPKHIDTSET DFNAAEGELI
     WCDRGDYPYD VIKRHAEYAL WQKYSDKKFI AVRYPFVIGK DDYTNRIRFY VEHVMEEKPM
     NIDNVDYQMG YIRSDEAGDF ISFLVDKEFE GAINGASNGT ISLREIINYV EDKTGKKAVM
     DKNGDDAPYN GEVEYSINTK LAQSLGFKFN NLNDYIYDLI DYYIDEINRS W
//