ID   A0A1T4W9W4_9CLOT        Unreviewed;       201 AA.
AC   A0A1T4W9W4;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Thiamine-phosphate pyrophosphorylase {ECO:0000313|EMBL:SKA73987.1};
GN   ORFNames=SAMN05428976_101323 {ECO:0000313|EMBL:SKA73987.1};
OS   Clostridium sp. USBA 49.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1881060 {ECO:0000313|EMBL:SKA73987.1, ECO:0000313|Proteomes:UP000190748};
RN   [1] {ECO:0000313|EMBL:SKA73987.1, ECO:0000313|Proteomes:UP000190748}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USBA 49 {ECO:0000313|EMBL:SKA73987.1,
RC   ECO:0000313|Proteomes:UP000190748};
RA   Peterson S.W.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Cofactor biosynthesis; thiamine diphosphate biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004948}.
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DR   EMBL; FUYD01000001; SKA73987.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T4W9W4; -.
DR   STRING; 1881060.SAMN05428976_101323; -.
DR   OrthoDB; 9815348at2; -.
DR   Proteomes; UP000190748; Unassembled WGS sequence.
DR   GO; GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd00564; TMP_TenI; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR036206; ThiamineP_synth_sf.
DR   InterPro; IPR022998; ThiamineP_synth_TenI.
DR   PANTHER; PTHR20857:SF15; THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME; 1.
DR   PANTHER; PTHR20857; THIAMINE-PHOSPHATE PYROPHOSPHORYLASE; 1.
DR   Pfam; PF02581; TMP-TENI; 1.
DR   SUPFAM; SSF51391; Thiamin phosphate synthase; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000190748};
KW   Thiamine biosynthesis {ECO:0000256|ARBA:ARBA00022977}.
FT   DOMAIN          5..180
FT                   /note="Thiamine phosphate synthase/TenI"
FT                   /evidence="ECO:0000259|Pfam:PF02581"
SQ   SEQUENCE   201 AA;  22106 MW;  BCD512BB348995DD CRC64;
     MSKKLYVVTN RKLIKNGSLE DKIKSSIKGG ADAIILREKD LSEKELYEIT IKILEYMDGN
     IPLIINESYK VGKISQTAGI HLSYESFMNF DKQYNKLLGV SIHSLEEGIA VENKGADYVI
     AGHIYNTSCK KGVPGRGITF LENICSVLTI PVIAIGGVNE NNVKEVLKCG ADGIAVMSSV
     MESENAEKVV YNLKNTINKM I
//