ID   A0A1T4WGQ4_9CLOT        Unreviewed;      1043 AA.
AC   A0A1T4WGQ4;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:SKA76138.1};
GN   ORFNames=SAMN05443428_101147 {ECO:0000313|EMBL:SKA76138.1};
OS   Caloramator quimbayensis.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Caloramator.
OX   NCBI_TaxID=1147123 {ECO:0000313|EMBL:SKA76138.1, ECO:0000313|Proteomes:UP000190105};
RN   [1] {ECO:0000313|EMBL:SKA76138.1, ECO:0000313|Proteomes:UP000190105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USBA 833 {ECO:0000313|EMBL:SKA76138.1,
RC   ECO:0000313|Proteomes:UP000190105};
RA   Peterson S.W.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
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DR   EMBL; FUYH01000001; SKA76138.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T4WGQ4; -.
DR   STRING; 1147123.SAMN05443428_101147; -.
DR   OrthoDB; 9772207at2; -.
DR   Proteomes; UP000190105; Unassembled WGS sequence.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR   Gene3D; 2.60.40.2220; -; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR041147; GH38_C.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF17677; Glyco_hydro38C2; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          513..590
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
SQ   SEQUENCE   1043 AA;  121120 MW;  1D6A2D12175CC3E5 CRC64;
     MYYVLERIQK ICNELKNYVY PKKVEITDYK MMEGNFLGME GINNSKGEWK DFKTGENWGG
     RDYHCWFKTS VSIPEDFAGK VVALNFKTFD EGWDAINPQF ILYINGEYIQ GLDINHREVI
     ISDCAEKGKV YEIDLHAYSG LIDRKAKLFG ELVVIDKSTR ELFFNLQVPV WVCEKLDKED
     KRRIDMLNVL NEAVNILDLR KPFSSGFYES INKANEYLRE EFYEKLCGHS EVIATCVGHT
     HIDVAWHWTV AQTREKVARS FSTVLKLMEH YPEYVFMSSQ PQLYKFLKED HPKVYEKVKQ
     KIKEGVWEAE GAMWLEADCN VTCGESLVRQ ILFGKRFFKE EFGIESEILW LPDVFGYSAA
     LPQILKKSDV NYFMTTKIAW NQFNKLPYDT FMWRGIDGTE ILTHFITTKD PYQDPKSHFT
     TYNGQIHPGA IIGAWDRYQQ KDINNDVLVS FGFGDGGGGA TYEMLEVARR LNKGIPGCPK
     VNMGTSLDYF KRLEKKVKGN KRLPKWVGEL YLEYHRGTYT SMARNKRDNR ISENLYTSAE
     KVSSFAKLLG KNYPQQKLNK GWENILLNQF HDILPGSSIK EVYDVTKEEY KEIIQNGKDI
     LCEGIEAIAA NINLNNKSLV VFNTLSFERN DIVVFDIPNN MKDVILIDEA GKEIVCQKIG
     KNRTVFFAEG IPPLGYKAYT IKEGSSKKES SIKVDKDIIE NEFFKISLDD KGQIKSFYDK
     KNNRELLKEG EILNVLLAFE DKPMNFDNWD IDIYYQEKMW KIDNIQSIEI VERGPVRAAL
     RIKRKFSDSI IIQNIYVYND IPRIDFNTYV DWKEHQVLLK AAFPIDINTS KATYEIQYGN
     IERPTHYNTS WDVARFEVVG QKWVDISEGG FGVSLLNDSK YGHDIKDGVM RLTLIKSGIE
     PNLTTDQEEH IFTYSLYPHA NDWRDANTAH MAYNLNVPLY TKIEDEHNGK LPEKLSIISV
     DKDNVMIEVV KKSEDSEDIL IRMYEFHNKR TNVKVSSFAE IKEVIECNLI ERDIQILKAD
     KNSFSFEIKP YEIKSFKLKL KSL
//