ID   A0A1T4XYU4_9BACT        Unreviewed;      1235 AA.
AC   A0A1T4XYU4;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Leucine-rich repeat (LRR) protein {ECO:0000313|EMBL:SKA94563.1};
GN   ORFNames=SAMN02745166_02182 {ECO:0000313|EMBL:SKA94563.1};
OS   Prosthecobacter debontii.
OC   Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales;
OC   Verrucomicrobiaceae; Prosthecobacter.
OX   NCBI_TaxID=48467 {ECO:0000313|EMBL:SKA94563.1, ECO:0000313|Proteomes:UP000190774};
RN   [1] {ECO:0000313|EMBL:SKA94563.1, ECO:0000313|Proteomes:UP000190774}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700200 {ECO:0000313|EMBL:SKA94563.1,
RC   ECO:0000313|Proteomes:UP000190774};
RA   Peterson S.W.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FUYE01000006; SKA94563.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T4XYU4; -.
DR   STRING; 48467.SAMN02745166_02182; -.
DR   OrthoDB; 243056at2; -.
DR   Proteomes; UP000190774; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR032171; COR.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR46652; LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR   PANTHER; PTHR46652:SF3; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 ISOFORM X1; 1.
DR   Pfam; PF16095; COR; 1.
DR   Pfam; PF08477; Roc; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52058; L domain-like; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS51450; LRR; 1.
PE   4: Predicted;
FT   DOMAIN          746..937
FT                   /note="C-terminal of Roc (COR)"
FT                   /evidence="ECO:0000259|Pfam:PF16095"
FT   DOMAIN          1053..1148
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|Pfam:PF13676"
FT   REGION          552..578
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1026..1046
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        561..576
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1235 AA;  138889 MW;  5750EA7AE126B070 CRC64;
     MASHPEGLSI ARQRIAEEKE KRTGFLDLGM LGLKEWPEEL WELGHLTGLN LGSGWPDNNG
     QWIYLGDELE ENQLPDKGIN WLHIPNLKRL FYCRDYLRGY AWQDISHLQV LTKLEELDFC
     GCNVRSLEPL SKLKLLKKLR CGSNPWADAT PLEQLQSLEA LDCCATNLTS LEPISKLVNL
     KELNISSIDL LDIRPIAQNN NLESIDFYET SITTGLEPLE CLLNLRHINC GGSGITDLGP
     IRNLSRLVKL VCSKNPINSL EPISDLINLL ELECYSINVT NLDALNGLEY LERLDCSYTK
     ISDLAALVGL DSLSHLDCSY TKICDLSVMS ALHSLQNLNC SNTKVSKLEP LCGLSYLHSL
     NCSNTQISNL DALSSLKSLR LLNCEKTGVD DLLPLVGLEC LESINISRTN VSDLKPLTML
     LGLKSIVASF VPIHSIPSEI IWSPVIQHLI LYVTCIQSVP REVLSPNSYT SCLESLRAHF
     QDLEAGEALL PDVKVMVLGN GRIGKTQICN RLRGLPFEAE SDSTHGITVT TTPLKWGGHS
     CPPCLPASVA DGLAHPPSET SGQECPRSSQ EAQAAKSRSE CPPHLLRLWD FGGQDIYHGT
     HALFMRSRAL FLLVWTPDSE NSETHVHKGM TFRNQPLPYW LAYIRHLAGV QSPVLVIQNQ
     CDAPADERLR PPVEDTLLQP FDLKKMLHYS AYNRRGHAAL EEALQDAIEH LRQTQGHAVI
     GKGRLAVKQH IEALQKADAE IPEVALKKNR TIARMHFQQI CDTCQGVSSP DHLLDYLHQT
     GIVFYQKGLF DDQIILDQAW ALEAVYAVFN REKCYKTLKQ IRGRFTRSLL ESLVWQQHSE
     EEQKLFLTMM KSCGICFVHR RGDQQRGIET EYIAPDLLPE YAEVEDEVAA QWDSTAVCDE
     VQMEVGFLHA GLMRGLLSRI GSEAGMTAVY WKDGVCLYEK KTRSHARIEQ RPVNRSDASP
     CSGIIHLRAY GGNSLQLLEM LTPWFWDEVK RAGCQTDGIL TTEHPLNLLA KDKRLTLKGG
     SEVVDEEAEI DTPPVEMKPD FTSPPRTQTT YGVSYAWNDA SQEIVNQLCD QAVAEHGVKI
     LRDVTGMGLG ESISKFMRTL TQQDRVFVIL SAKYLQSPFC MYELWQIWIN CRADDEAFRR
     CVRVYRLPDA AMMSPIERAR CAKYWRDQFK ELDDLVRVEG ADLLGELDFK RYKLMQDFAN
     RVGDILAVIA DMLLPQDFSQ LEQHGFGDAE RESGE
//