ID A0A1T4YS22_9ACTN Unreviewed; 372 AA.
AC A0A1T4YS22;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN ORFNames=SAMN06295964_0621 {ECO:0000313|EMBL:SKB04569.1};
OS Aeromicrobium choanae.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Aeromicrobium.
OX NCBI_TaxID=1736691 {ECO:0000313|EMBL:SKB04569.1, ECO:0000313|Proteomes:UP000191040};
RN [1] {ECO:0000313|EMBL:SKB04569.1, ECO:0000313|Proteomes:UP000191040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=9H-4 {ECO:0000313|EMBL:SKB04569.1,
RC ECO:0000313|Proteomes:UP000191040};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000799};
CC -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00005297}.
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DR EMBL; LT796768; SKB04569.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T4YS22; -.
DR STRING; 1736691.SAMN06295964_0621; -.
DR OrthoDB; 9806579at2; -.
DR Proteomes; UP000191040; Chromosome i.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR019999; Anth_synth_I-like.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR004561; IsoChor_synthase.
DR NCBIfam; TIGR00543; isochor_syn; 1.
DR PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR PRINTS; PR00095; ANTSNTHASEI.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235}.
FT DOMAIN 103..362
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
FT REGION 190..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 372 AA; 39376 MW; 51D2AF72E33D7D0D CRC64;
MNPTLEPTRS ASALRRSPLV FAGSDPFAAD EVRRTLHART GDPDLACRVL RALEPGERAV
VSAAFRADGP VVAHFVTPRE LEHAEPSPVE ARVHDVVPEP ARSAYVDLVA TALDRIEGTD
VAKVVLGRCL EVHSSPALSP AEVTATLLDR RPGRYVFCLP LDDRPDARWL VGASPELLVR
RRGAELASTP LAGSVPRSPD PDEDSRRAAA LADSAKDLAE HAFVVDHIAA ALSPVCEWLE
VPAVPEVLAT DSMWHLASPI RGRLRAPEDL TALDLAQLLH PTPAVGGVPT PTATELIDEL
EGPDLRGPFG GFVGWMDADG DGELAVTIRA GVLDGERLRL FAGAGIVAGS DPLAEADETA
AKLSTMTRAV GL
//
