ID A0A1T5AEA7_9SPHI Unreviewed; 757 AA.
AC A0A1T5AEA7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Monovalent cation:H+ antiporter-2, CPA2 family {ECO:0000313|EMBL:SKB33304.1};
GN ORFNames=SAMN05661099_0630 {ECO:0000313|EMBL:SKB33304.1};
OS Daejeonella lutea.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Daejeonella.
OX NCBI_TaxID=572036 {ECO:0000313|EMBL:SKB33304.1, ECO:0000313|Proteomes:UP000189981};
RN [1] {ECO:0000313|Proteomes:UP000189981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22385 {ECO:0000313|Proteomes:UP000189981};
RA Varghese N., Submissions S.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. {ECO:0000256|ARBA:ARBA00005551}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FUYR01000001; SKB33304.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T5AEA7; -.
DR STRING; 572036.SAMN05661099_0630; -.
DR OrthoDB; 9781411at2; -.
DR Proteomes; UP000189981; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR PANTHER; PTHR42751:SF3; NA(+)_H(+) ANTIPORTER; 1.
DR PANTHER; PTHR42751; SODIUM/HYDROGEN EXCHANGER FAMILY/TRKA DOMAIN PROTEIN; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02080; TrkA_C; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189981};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 32..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 501..522
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 528..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 585..669
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 671..757
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 757 AA; 83920 MW; BC406F947E0A4476 CRC64;
MGHLPDLIRD LALILIAGAI TTLIFRKIKQ PLVLGYIIAG FLVGPHFHLL PTVADNENIE
ILAEIGVIFL LFNLGLEFSF KKLLRVGGSA SITAFVEIVF ITVAGYFTGK LMGWSTMDSL
FLGGMLASSS TTIIIRAFDE LGVKTKQYAR IVFGVLVVED IVVILLMVLL STIAVTKQFA
GGEIIYTISK LLFFLALWFI GGIFLIPTLL KKAKSLIDDE TLLIISIGLC LGMVVLATQV
GFSAELGAFI MGSILAETTS AEKVEHVTKP VKDLFGAVFF VSVGMMIDPE AIVQYGWPVV
IVTLLTLFGK LFSTTIGAVI SGQPLKQSVQ VGMSMAQIGE FAFIVATLGL SLGVISDFLF
PVAVGASAIT TFTTPYLIRF SGPFYDFLER VLPARLVKRL NNYSSGTQAI QAENDWKIVL
KSYGMIILTN GVILLALIVF SINFFMPFLS EQIKDATTRS TIGLLVSLIF ASPFLWALMA
KRPNNMAYKE MWLEKKYSRG PLLLLEIARI LIGGLLVAFW VFELFDTEIA IFIAVPIILV
IIFVFTKRIQ AFYQRIELRF LGNLNAREDD EYNSLDANVS RKNAALEAKL TPWDAHIVQL
EVPPGADYIG RTLPELAWRE KYGVNLVYVK RGDKMILAPD RNSILLPFDQ VGIIATDDQI
QSFKPVFDSV VHVESTVMHV NDISLQRIVV NEYTRLKGVT IRNSGLRERT NGLIIGIERN
NERILNPEST TVFEWDDIVW IVGERKKIQE LSSRNAG
//
