ID   A0A1T5BBM5_9SPHI        Unreviewed;       158 AA.
AC   A0A1T5BBM5;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Multicomponent Na+:H+ antiporter subunit E {ECO:0000313|EMBL:SKB44467.1};
GN   ORFNames=SAMN05660841_00530 {ECO:0000313|EMBL:SKB44467.1};
OS   Sphingobacterium nematocida.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Sphingobacterium.
OX   NCBI_TaxID=1513896 {ECO:0000313|EMBL:SKB44467.1, ECO:0000313|Proteomes:UP000190150};
RN   [1] {ECO:0000313|Proteomes:UP000190150}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 24091 {ECO:0000313|Proteomes:UP000190150};
RA   Varghese N., Submissions S.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E
CC       family. {ECO:0000256|ARBA:ARBA00006228}.
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DR   EMBL; FUZF01000002; SKB44467.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T5BBM5; -.
DR   STRING; 1513896.SAMN05660841_00530; -.
DR   OrthoDB; 9800498at2; -.
DR   Proteomes; UP000190150; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR002758; Cation_antiport_E.
DR   PANTHER; PTHR34584; NA(+)/H(+) ANTIPORTER SUBUNIT E1; 1.
DR   PANTHER; PTHR34584:SF1; NA(+)_H(+) ANTIPORTER SUBUNIT E1; 1.
DR   Pfam; PF01899; MNHE; 1.
DR   PIRSF; PIRSF019239; MrpE; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        50..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   158 AA;  18809 MW;  07F99D0D2D3C1941 CRC64;
     MIKQFLMNLL LSFIWVALTG SMYYTNFVFG FLLGFAILWI MSRNDGDRRY FYKVPRIVSF
     VFYFLYQMIK ANIQVAYDVM TPRYFMRPGV VRYPLNAQTE MEINILSMMI SLTPGTLILD
     ISEDRKTMYI HVMYLDDPKK FVQDTKTGLE RRLLEALR
//