ID A0A1T5ERG0_9BACT Unreviewed; 1462 AA.
AC A0A1T5ERG0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN03080601_01368 {ECO:0000313|EMBL:SKB86448.1};
OS Alkalitalea saponilacus.
OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Marinilabiliaceae;
OC Alkalitalea.
OX NCBI_TaxID=889453 {ECO:0000313|EMBL:SKB86448.1, ECO:0000313|Proteomes:UP000191055};
RN [1] {ECO:0000313|EMBL:SKB86448.1, ECO:0000313|Proteomes:UP000191055}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24412 {ECO:0000313|EMBL:SKB86448.1,
RC ECO:0000313|Proteomes:UP000191055};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FUYV01000006; SKB86448.1; -; Genomic_DNA.
DR STRING; 889453.SAMN03080601_01368; -.
DR Proteomes; UP000191055; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF07494; Reg_prop; 5.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 3.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000191055};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 900..924
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 946..1163
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1207..1322
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1359..1458
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT MOD_RES 1255
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1462 AA; 166453 MW; 4C2124F745F38192 CRC64;
MLIAVMPVVL FSQVSENYTW TRYTTEDGLS QNTVMSIHQD KKGYMWYATW DGLSRFDGYN
FTTYKVRPGD NVFLTSSRID RLLEDKYGYI WLWAYGKNVS WFDPSTEEFQ NVPDYFRDVT
QVREIVTLHN GVTWLITEEE GGARIITDPV TKEFRSNEYS KNSGLLQSNK IRKVFADSNG
NEWILTDNGI SVINNGGEDL SSYFHHSVYT GSNNFNIFYT ASEFDDEIWF GANSGKVWRY
VKNGSRFISL QVPSVSGIVS IHTISDHEYF LATASDGLFI HNTLTGNFAH YNGHLISGNQ
EEIIFDTYQD SFGDIWIQQS SNSVIQYNVE NSEVVSHTVG SVTRDGIGGP DFMIHEDVNG
TLWIHPQGGG VYYYDRIQNK LQPFFSQESS MLTFSDRLHS MYSDRQGNLW MSTRARGLEK
FVFHSSQFQI LEVNTKPQFI SDNDVRAILE DSRGYMWVST KAGKVALFNS ESDLIGYLGP
DGKLHADIVF SNANVYTILE DRHGNIWLGT KGKGLVKAHV SQQGAGISYD LVHFRNDPGN
INSLSHDDIY HIHEDEKGRI WLATYGGGIN LLNYTGDGGY EFINSNNSFN NYPITKCYSV
RYITTCNNAK VWVGTTNGLV VFDNPDNAMD DINFRHFTYM PGDSLCLSNN DVHNILITSK
GEVFLATFGG GLNELIDPVN RSDFRFKSYT KESGLQTDVL LSAVEDPNGR IWIATENGIS
QFDRETKDFR NFNKTDFSRA LSFSEGSAQL ASNGQIWFGT NNGVLRFHPD SISRSNFVPP
IVLTEFRVLN KRISPGKGEV LKKHIDATHE IKLRHNQNII SFGFAALDMK YPEAVKYAAM
LEGFENEWVF LDKQRLVNYT NLPSGDYKLR VRSTNSDGIW VDNEKSVSIF ISPSFWVTTW
AYLTYFTLFF IIAGLSVYVL FTIYRLRHRI TMEQQVSEMK LDFFTNISHE LRTPLTLISG
PLEQILNDPS VKDKHKESLQ VVERNSSRML RLINQILDFV KISHNKMKMT VEMIPAGEFV
NRVMDNFRLM AIDHQIEFTL NDQSGGDYIW ADADKFEKII FNLLSNAFKY ISGGKYIKVR
IESDVERMRI YVIDNGAGIV ENKKSSLFNR FESSLVKGFS RVPSTGIGLS IVKELVELHK
GQIQVENTES RGTTFILSLK KGLSHFGEDV EILDETDGTE TALEQGLYSE KEATEGMTLD
ENNALPYLLL VEDNIEVRKF ILSILKHDYN VIEAGDGEEG FEKAQKYQPD IIISDLMMPV
KDGMELLRDI RDNINTSHIP FIMLTAKTNE ESQLEGLSRG ADDYITKPFS PAYLQSRVIN
LLDQRRKLQL LYQGKSTVAK SDLEPDMPEV TSLDEKFLSG LKALMEENME NSDLVVEDLV
GEMALSRSVF FKKLKALTGL APIEYIKEMR LKRAAQLISI GQHNMTQIAF MVGMNDSRYF
SKCFKQKYGM TPSEYKVRMS NQ
//
