ID   A0A1T5F6M7_9FIRM        Unreviewed;       478 AA.
AC   A0A1T5F6M7;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Alanine or glycine:cation symporter, AGCS family {ECO:0000313|EMBL:SKB91781.1};
GN   ORFNames=SAMN06296386_10912 {ECO:0000313|EMBL:SKB91781.1};
OS   Lachnospiraceae bacterium.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1898203 {ECO:0000313|EMBL:SKB91781.1, ECO:0000313|Proteomes:UP000191179};
RN   [1] {ECO:0000313|EMBL:SKB91781.1, ECO:0000313|Proteomes:UP000191179}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KH1P17 {ECO:0000313|EMBL:SKB91781.1,
RC   ECO:0000313|Proteomes:UP000191179};
RA   Peterson S.W.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
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DR   EMBL; FUZG01000009; SKB91781.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T5F6M7; -.
DR   OrthoDB; 9804874at2; -.
DR   Proteomes; UP000191179; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Reference proteome {ECO:0000313|Proteomes:UP000191179};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        15..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        71..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        100..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        149..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        197..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        228..248
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        254..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        321..345
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        365..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        406..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        433..454
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   478 AA;  51023 MW;  5110D95F7DD55623 CRC64;
     MLNTISDINN SVNSFIWGVP AMICIIGVGL LLSFRTKFLQ IRKFPYALRV TIGRMFSKTE
     SREGAITPFQ AVCTALAATI GTGNIAGVAG ALALGGPGAI FWMWCSALLG MCTKFAEVTL
     AVKFREKNKD GEFVGGPMYY IKNGLSKKWH WLAVIYSILG ILTVFGTGNA TQVNTITVAV
     NEALINFNVI NEAQLPASKL IIGVIIAILV ALILLGGIKR IGNVTEKLVP FMALFYVLIS
     FGVIVLHIRE IPAIFASIFE GAFNPHAVTG GIVGSFFLSM KKGVSRGIFS NEAGLGTGSI
     AHACADTNEP VKQGLFGIFE VFSDTIVVCT MTALVILCSG VTINYGEAAG AELTISGFSS
     TYGNWISIFT AIAMCCFAFS TVLGWGLYGQ RCIEFLFSSA WTKPFLIVYS LVAVVGATID
     LGLVWAISDT CNGLMVIPNL IAMFLLSGTV VKLVNVYFSK NTETLSDDSA SDTPDPVL
//