ID A0A1T5FFF4_9BACT Unreviewed; 456 AA.
AC A0A1T5FFF4;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05660293_03141 {ECO:0000313|EMBL:SKB94862.1};
OS Dyadobacter psychrophilus.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Dyadobacter.
OX NCBI_TaxID=651661 {ECO:0000313|EMBL:SKB94862.1, ECO:0000313|Proteomes:UP000190897};
RN [1] {ECO:0000313|EMBL:SKB94862.1, ECO:0000313|Proteomes:UP000190897}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22270 {ECO:0000313|EMBL:SKB94862.1,
RC ECO:0000313|Proteomes:UP000190897};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FUZA01000003; SKB94862.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T5FFF4; -.
DR STRING; 651661.SAMN05660293_03141; -.
DR OrthoDB; 594725at2; -.
DR Proteomes; UP000190897; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR45436:SF5; SENSOR HISTIDINE KINASE TRCS; 1.
DR PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SKB94862.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 6..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 179..232
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 240..456
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 456 AA; 51689 MW; CDC73C857C97D856 CRC64;
MNIKSRLTLL FTMLVGSIMA LFCLSIYYFY DQYREKQFYS FLNERAQTIA QLVEASQDIS
KADIEKIEKE NNTIFLNEEI TIYDGADSLI FTGGNEKFTL SKTILAEARA GREIRTKHDK
KEAIIIRHVL QDHRKPWVVM AVANDVPGMN QLKRLREILV IGWLLSLILV GVAGWQFAND
AIKPVSDIIS QVNNISAGNL HEKVTVGREK DELAALAQTF NQMLGRLEIA FLAQKNFVSH
ASHELRTPLA LIMSEAELSL MKERASEEYK VALKGIWSEA KEMNELVSRL LELARTEEHA
FRVTFSKIRV DEVLWQAKAS VQQKNPGYEV HIHYDKIPED EEQLKRYGDE SLLKTAFMNL
MDNACKYSNN KTVNVFLKIQ KDLIQVDFKD VGVGIASDEL PFIFDTFYRS ATTISKAGYG
IGLALTKRII NMQGASIEVE SALGAGTTFI LKFPPF
//
