ID A0A1T5FKQ0_9FIRM Unreviewed; 364 AA.
AC A0A1T5FKQ0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Diguanylate cyclase (GGDEF) domain-containing protein {ECO:0000313|EMBL:SKB96781.1};
GN ORFNames=SAMN06296386_11137 {ECO:0000313|EMBL:SKB96781.1};
OS Lachnospiraceae bacterium.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1898203 {ECO:0000313|EMBL:SKB96781.1, ECO:0000313|Proteomes:UP000191179};
RN [1] {ECO:0000313|EMBL:SKB96781.1, ECO:0000313|Proteomes:UP000191179}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH1P17 {ECO:0000313|EMBL:SKB96781.1,
RC ECO:0000313|Proteomes:UP000191179};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FUZG01000011; SKB96781.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T5FKQ0; -.
DR OrthoDB; 9804955at2; -.
DR Proteomes; UP000191179; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000191179};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 229..359
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT COILED 168..195
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 364 AA; 41805 MW; 395075D4F1E84178 CRC64;
MKQLEANMRR RVLRTIFIFT WLFAAIDIGF YIVDIFTGFR GVDRVMYPLV RILLPFIINA
GAWFGTMQVV RSEKCSGHLK NLIVCGCLMT ICGTMVVFHS SFTLLWVVPS IVLLLASVFH
DTIIQRDLFF YNLLIIFITV IEAVFENPEK VLIIAENATV VLLLCLFIFS AASLMQQYND
ELARLNKEIY RRQADYREKF RMDFLTGVYS KAYFFEKAAE IMDNAADRHP IVVGIIDLDH
FKRVNDTYGH ENGDLVLEAL GTLLREYQTE TLCIGRFGGE EFVMVFDEES LMQGWLIMDE
IRTRFAEEKF TFTPSRMTLS GGVAVFTEPV QIEEAIAKAD QALYQSKTMG RNRITRVENE
TIGA
//
