ID A0A1T5FUX1_9FLAO Unreviewed; 445 AA.
AC A0A1T5FUX1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Zinc metalloprotease {ECO:0000256|RuleBase:RU362031};
DE EC=3.4.24.- {ECO:0000256|RuleBase:RU362031};
GN ORFNames=SAMN05660477_02302 {ECO:0000313|EMBL:SKB99854.1};
OS Soonwooa buanensis.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Soonwooa.
OX NCBI_TaxID=619805 {ECO:0000313|EMBL:SKB99854.1, ECO:0000313|Proteomes:UP000191112};
RN [1] {ECO:0000313|EMBL:SKB99854.1, ECO:0000313|Proteomes:UP000191112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22323 {ECO:0000313|EMBL:SKB99854.1,
RC ECO:0000313|Proteomes:UP000191112};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU362031};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase M50B family.
CC {ECO:0000256|ARBA:ARBA00007931, ECO:0000256|RuleBase:RU362031}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FUYZ01000008; SKB99854.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T5FUX1; -.
DR STRING; 619805.SAMN05660477_02302; -.
DR OrthoDB; 9782003at2; -.
DR Proteomes; UP000191112; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00989; PDZ_metalloprotease; 1.
DR CDD; cd06163; S2P-M50_PDZ_RseP-like; 2.
DR Gene3D; 2.30.42.10; -; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR004387; Pept_M50_Zn.
DR InterPro; IPR008915; Peptidase_M50.
DR NCBIfam; TIGR00054; RIP metalloprotease RseP; 1.
DR PANTHER; PTHR42837:SF2; MEMBRANE METALLOPROTEASE ARASP2, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR42837; REGULATOR OF SIGMA-E PROTEASE RSEP; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF02163; Peptidase_M50; 1.
DR SMART; SM00228; PDZ; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU362031};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362031};
KW Metal-binding {ECO:0000256|RuleBase:RU362031};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000256|RuleBase:RU362031};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:SKB99854.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000191112};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362031};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362031};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU362031}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 102..126
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 368..388
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 417..438
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT DOMAIN 190..275
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
SQ SEQUENCE 445 AA; 50053 MW; 50DDBB64DE189B65 CRC64;
MAPEQLFQFI LSISILVILH ELGHFIPAKL FKTKVEKFYL FFDPWFSIAK KKIGETEYGI
GWLPFGGYVK IAGMVDESMD TDQLKKPAEP WEFRSKPAWQ RLIIMLGGVT VNFFLAWLIY
SCLSYFKGEK YYDNAKFEAG IAVTSEGAKM GLKTGDKILK IDGKPAERMQ TSIMNMLFAN
NVTVLRDGKE VTFPVNEDGV AEVLKANEAK LYFSNRFPAV VDSIAPNLPA AAMGLKKGDK
IIEINNQPTQ YYDQVTTALL QNAGKPISVK VDRNNQVETL QTTLGKDGKL GFGINGALAQ
KELDKTQVVK NYTFLESIPR GFERTIDVLV MQVKQFKIIF NSKTEGYKKV SGPIGIIKQM
PETINWEFFW SFTAMFSVWL AFLNLIPIPG LDGGHVVFTL WEMITGKPVP QKVLENAQMI
GVIFLLGLMV LIFGNDIVKW ITGKF
//
