ID   A0A1T5ICX6_9CLOT        Unreviewed;       466 AA.
AC   A0A1T5ICX6;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Alanine or glycine:cation symporter, AGCS family {ECO:0000313|EMBL:SKC36873.1};
GN   ORFNames=SAMN02194393_00214 {ECO:0000313|EMBL:SKC36873.1};
OS   Maledivibacter halophilus.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Maledivibacter.
OX   NCBI_TaxID=36842 {ECO:0000313|EMBL:SKC36873.1, ECO:0000313|Proteomes:UP000190285};
RN   [1] {ECO:0000313|EMBL:SKC36873.1, ECO:0000313|Proteomes:UP000190285}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M1 {ECO:0000313|EMBL:SKC36873.1,
RC   ECO:0000313|Proteomes:UP000190285};
RA   Peterson S.W.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
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DR   EMBL; FUZT01000001; SKC36873.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T5ICX6; -.
DR   STRING; 36842.SAMN02194393_00214; -.
DR   OrthoDB; 9804874at2; -.
DR   Proteomes; UP000190285; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Reference proteome {ECO:0000313|Proteomes:UP000190285};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        20..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        80..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        106..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        154..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        185..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        218..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        257..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        312..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        355..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        397..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        421..441
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   466 AA;  50588 MW;  871183B9D6370360 CRC64;
     MKEAVVNFIN YMTGLLWGPF MLILLLGGGI FLTIRLNFIQ FRYFKYMWNQ TFGNLFKKQE
     KQDSEDAHGT VTPFQAVTTA LASTVGAANI VGVPVAIFFG GPGAVFWMWV TALFGMITKY
     VEVVLGVMYR EKNADGEYVG GPMYYLKNGL KSKFLGNAYA FIFMLTIVSG IMVQANSAAG
     SAESLGINTT ISGIIITLIV GIIVVGGVKR VGKVSEKFVP FMASLYVLGC LIIIFANITA
     IPGVFVSIFK SAFSPQAAVG GFAGSTIALT MRWGIARGAY SNEAGMGSAP IAHAAAKTDH
     PVRQGMWGMF SVFFDTLLIC TMTALVILST GIWTNGDIGA AAMTAEAFND FYGKIGGGLV
     SFSVLLFVIS TIYVILFYGE RLAEYLFGKT FSLIMRYVYL GACFAGAVGG LRFLWIFLDF
     LFGLAVIPNM IGVLFLSGVV AKKTKEFFTS EKYYLKDVKM KKSLND
//