ID   A0A1T5IEV7_9MICO        Unreviewed;       771 AA.
AC   A0A1T5IEV7;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Formate dehydrogenase major subunit {ECO:0000313|EMBL:SKC37726.1};
GN   ORFNames=SAMN04324258_0441 {ECO:0000313|EMBL:SKC37726.1};
OS   Krasilnikoviella flava.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC   Promicromonosporaceae; Krasilnikoviella.
OX   NCBI_TaxID=526729 {ECO:0000313|EMBL:SKC37726.1, ECO:0000313|Proteomes:UP000189777};
RN   [1] {ECO:0000313|EMBL:SKC37726.1, ECO:0000313|Proteomes:UP000189777}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21481 {ECO:0000313|EMBL:SKC37726.1,
RC   ECO:0000313|Proteomes:UP000189777};
RA   Peterson S.W.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mo-bis(molybdopterin guanine dinucleotide);
CC         Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
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DR   EMBL; FUZQ01000001; SKC37726.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T5IEV7; -.
DR   STRING; 526729.SAMN04324258_0441; -.
DR   OrthoDB; 9759518at2; -.
DR   Proteomes; UP000189777; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   CDD; cd02787; MopB_CT_ydeP; 1.
DR   CDD; cd02767; MopB_ydeP; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR037951; MopB_CT_YdeP.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR010046; Mopterin_OxRdtse_a_bac.
DR   InterPro; IPR041953; YdeP_MopB.
DR   NCBIfam; TIGR01701; Fdhalpha-like; 1.
DR   PANTHER; PTHR43105:SF4; PROTEIN YDEP; 1.
DR   PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   PIRSF; PIRSF000144; CbbBc; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189777}.
FT   DOMAIN          125..502
FT                   /note="Molybdopterin oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00384"
FT   DOMAIN          657..763
FT                   /note="Molybdopterin dinucleotide-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01568"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   771 AA;  82665 MW;  D50177B6E4274628 CRC64;
     MTTQQPEGTR PGDPADTQPD EVRPPKDWAA GVPGIVHALV PALRDMGPAR TARLLLAMNH
     REGFDCMSCA WPDPDRRKPA EFCENGAKAV TWEATPLVVR PEFWAEHPVS DLATRTEHWL
     GQQGRLAAPV HKPAGSDHYV PVSWDEAFAI LADRLGGLDS PDQASFYTSG RTSNEAAFVY
     QLFVRAFGTN NLPDCSNMCH ESTGAALGET IGVGKATITY DDFALADLIV IMGQNPGTNH
     PRMLTALEEA KRNGASIVAV NPLPEAGLKR YKNPQTARGL AGRGTELADQ FLQIRLGGDM
     ALLQAVSKRV LDAEAAAPGT VLDHAFLAEH ASGLEALAAH LADLDEDAVL AATGLTSAEI
     DELADRYVRA ERVIVTWAMG LTQHTKAVPT IKEIVNLLLL RGNIGRPGAG ASPIRGHSNV
     QGDRTMGIWE QMPDSFLDAL DAEFGITSPR EHGLDAVGTV EAMAAGRVRV LVALGGNLVG
     AISDTGAAEE AVRRADLTVQ ISTKLNRSHA VVGREALILP TLGRTDVDRQ ASGEQMVSVE
     DTVCAVHASH GKVEPVAKGL LSEVSIVTRM ARAVLGARPG GPGPVDWAAM ERDYDVIREH
     VARVVPGCED YNAKLRRPNG FRLPHGPRDS RTFPTDDGRA HLTVNELAHV ECPPGRLLLQ
     TVRAHDQFNT TIYRRDDRYR GIKGGRAVVL VNPDDLAELG IADGTTVDVH GEYHDGVDRV
     LRGQRVVAYP TARGCAAAYF PEANVLVPLG ATAETSRTPV SKAVVVRLEP A
//