ID   A0A1T5IY22_9BACT        Unreviewed;       353 AA.
AC   A0A1T5IY22;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=A/G-specific DNA-adenine glycosylase {ECO:0000313|EMBL:SKC44109.1};
GN   ORFNames=SAMN06298214_0707 {ECO:0000313|EMBL:SKC44109.1};
OS   Bacteroidales bacterium WCE2004.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales.
OX   NCBI_TaxID=1945890 {ECO:0000313|EMBL:SKC44109.1, ECO:0000313|Proteomes:UP000189975};
RN   [1] {ECO:0000313|Proteomes:UP000189975}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WCE2004 {ECO:0000313|Proteomes:UP000189975};
RA   Varghese N., Submissions S.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the Nth/MutY family.
CC       {ECO:0000256|ARBA:ARBA00008343}.
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DR   EMBL; FUZR01000001; SKC44109.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1T5IY22; -.
DR   STRING; 1945890.SAMN06298214_0707; -.
DR   OrthoDB; 9802365at2; -.
DR   Proteomes; UP000189975; Unassembled WGS sequence.
DR   GO; GO:0019104; F:DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd03431; DNA_Glycosylase_C; 1.
DR   CDD; cd00056; ENDO3c; 1.
DR   Gene3D; 1.10.1670.10; Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal); 1.
DR   Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR   InterPro; IPR005760; A/G_AdeGlyc_MutY.
DR   InterPro; IPR011257; DNA_glycosylase.
DR   InterPro; IPR003265; HhH-GPD_domain.
DR   InterPro; IPR023170; HhH_base_excis_C.
DR   InterPro; IPR044298; MIG/MutY.
DR   InterPro; IPR029119; MutY_C.
DR   NCBIfam; TIGR01084; mutY; 1.
DR   PANTHER; PTHR42944; ADENINE DNA GLYCOSYLASE; 1.
DR   PANTHER; PTHR42944:SF1; ADENINE DNA GLYCOSYLASE; 1.
DR   Pfam; PF00730; HhH-GPD; 1.
DR   Pfam; PF14815; NUDIX_4; 1.
DR   SMART; SM00478; ENDO3c; 1.
DR   SUPFAM; SSF48150; DNA-glycosylase; 1.
PE   3: Inferred from homology;
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189975}.
FT   DOMAIN          36..185
FT                   /note="HhH-GPD"
FT                   /evidence="ECO:0000259|SMART:SM00478"
SQ   SEQUENCE   353 AA;  38902 MW;  CDF5517F804F0E5E CRC64;
     MSPFSETILS WYAAYGRDLP WRRTADPYAI WLSEIILQQT RIAQGQAYWE RFMERFPTVE
     ALAGASEDEV LRLWQGLGYY SRARNLHAAA RQVAALGHFP DTLDGIKALK GVGDYTAAAI
     GSIAFGLPAA VVDGNVYRVL ARHYGIATPV GSTAAKKEFS ALAQSLLPAD RPGDFNQGMM
     DFGALQCTPA APLCPLCPLA GSCAALATGA VDRLPVKEKG AAVQERRFDY VYVRFRGRTA
     IRRRGPGDIW AGLYEPLVCD QRLDGVAYDG GRIPRNPLGR FAPTASDQLP KDAMLLKSGV
     KHQLTHRTLL VDFYLWEPAG EPTLPDGYIW IDEAELDRYA KPRLFELLLE SLP
//