ID A0A1T5PC63_9BACT Unreviewed; 302 AA.
AC A0A1T5PC63;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=DNA-3-methyladenine glycosylase II {ECO:0000256|ARBA:ARBA00012000};
DE EC=3.2.2.21 {ECO:0000256|ARBA:ARBA00012000};
GN ORFNames=SAMN05660461_6253 {ECO:0000313|EMBL:SKD10344.1};
OS Chitinophaga ginsengisegetis.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Chitinophaga.
OX NCBI_TaxID=393003 {ECO:0000313|EMBL:SKD10344.1, ECO:0000313|Proteomes:UP000190166};
RN [1] {ECO:0000313|EMBL:SKD10344.1, ECO:0000313|Proteomes:UP000190166}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18108 {ECO:0000313|EMBL:SKD10344.1,
RC ECO:0000313|Proteomes:UP000190166};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-
CC methylguanine, 7-methylguanine and 7-methyladenine.; EC=3.2.2.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000086};
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DR EMBL; FUZZ01000006; SKD10344.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1T5PC63; -.
DR STRING; 393003.SAMN05660461_6253; -.
DR Proteomes; UP000190166; Unassembled WGS sequence.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0008534; F:oxidized purine nucleobase lesion DNA N-glycosylase activity; IEA:InterPro.
DR GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd00056; ENDO3c; 1.
DR Gene3D; 3.30.310.20; DNA-3-methyladenine glycosylase AlkA, N-terminal domain; 1.
DR InterPro; IPR037046; AlkA_N_sf.
DR InterPro; IPR011257; DNA_glycosylase.
DR InterPro; IPR003265; HhH-GPD_domain.
DR InterPro; IPR012904; OGG_N.
DR PANTHER; PTHR43003; DNA-3-METHYLADENINE GLYCOSYLASE; 1.
DR PANTHER; PTHR43003:SF12; DNA-3-METHYLADENINE GLYCOSYLASE; 1.
DR Pfam; PF00730; HhH-GPD; 1.
DR Pfam; PF07934; OGG_N; 1.
DR SMART; SM00478; ENDO3c; 1.
DR SUPFAM; SSF48150; DNA-glycosylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000190166}.
FT DOMAIN 136..300
FT /note="HhH-GPD"
FT /evidence="ECO:0000259|SMART:SM00478"
SQ SEQUENCE 302 AA; 34578 MW; CCF7D6DC7F1EFAD1 CRC64;
MALQKIKIPI NDPAHFSFEE CLRFLGRSDK ECLHYIHHGK VRRMLLSEGE PVVVEIAPGS
KNNFLEVTVL APAGEAVAEA PIIRYITHWW HLDANLQPFY QYTQTDPLLK GLAEKYNGLR
LIGMPDLFEA ITWPVIGQQI NLAFAYTLRQ RFIRQFGYHV VVDNTDFYLY PHPKVIAALT
PDQLTPMQFS RSKALYLVET ARQMASGALS EATLDTMSYE AARESLVAMK GIGNWSANYA
LMKYRRFPQS VLLEDVGLQN AIKNRLNLEA KPSMPALQEY TRPWKEHAAY ATFYLWRSLL
PQ
//
