ID A0A1U7CUN3_9BACT Unreviewed; 847 AA.
AC A0A1U7CUN3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN Name=uvrA_2 {ECO:0000313|EMBL:APW62660.1};
GN ORFNames=BSF38_04210 {ECO:0000313|EMBL:APW62660.1};
OS Paludisphaera borealis.
OC Bacteria; Planctomycetota; Planctomycetia; Isosphaerales; Isosphaeraceae;
OC Paludisphaera.
OX NCBI_TaxID=1387353 {ECO:0000313|EMBL:APW62660.1, ECO:0000313|Proteomes:UP000186309};
RN [1] {ECO:0000313|Proteomes:UP000186309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX4 {ECO:0000313|Proteomes:UP000186309};
RA Ivanova A.;
RT "Comparative genomics of four Isosphaeraceae planctomycetes: a common pool
RT of plasmids and glycoside hydrolase genes.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; CP019082; APW62660.1; -; Genomic_DNA.
DR RefSeq; WP_076348918.1; NZ_CP019082.1.
DR AlphaFoldDB; A0A1U7CUN3; -.
DR STRING; 1387353.BSF38_04210; -.
DR KEGG; pbor:BSF38_04210; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000186309; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 3.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000186309};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022771};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 507..836
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 826..847
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 847 AA; 91295 MW; 6234B9EC8409771F CRC64;
MSSAADAEPS AAIAIRGARV HNLRNVDLDV PRHRLVVLTG VSGSGKSSLA FDTIFAEGQR
RYIECLSSYA RQFLDQLERP DVDQIDGLPP TVAIDQRAGQ SSPRSTVGTL TEINDYLRLM
YSRLGAPHCP NCGLPIHSQT PEQMAATVMA FPPGRRLMVL APLVRAKKGA HAEVFQAIRR
AGLIRARVDG EVVEVADEPP KLAKTKNHSI DAVVDRLVIR EGIGPRLAES LNMALKLSEG
LVTITAEVDG AWQDHLLSIH LACPGCGTSL PTLEPRAFSF NSPQGACPTC EGLGIVPDGS
IEGEGDDDEI PCPDCQGSRL RPETRSVRID GRSIDQVFDM AIDEASGFFE RLRFAEADQA
VATPLLREIQ GRISFMSNVG LGYLALGRGS RTLSGGELQR VRLATQLGSG LVGVCYVLDE
PTTGLHPRDT GRLLAGLRDL EAQGNSVLVV EHDEAVIRAA DWIVDIGPGA GPDGGTIVDS
GTPDHIASSS VSITGRYLRG DVPTTRRQTE RLGQTPGWIT IRGASVHNLK GDEARIPLGT
LTCVTGVSGS GKSTLVHDVL ARGFRRRDRP SARELPGLGQ IEGWEPLTAL IEVDQSPIGR
TPRSTPATFT GVFDQIRRVF ATTREARMRG YGAPRFSFNV KGGHCETCEG QGRRRIPMQF
LPDLFVVCEE CQGKRFNRQT LEVLFKDKSI GDVLNLRVDE ARAFFDAQPR VLPGLIALHD
VGLGYLTLGQ SSTTLSGGEA QRVKLAAQLG RPTFGKNLYI LDEPTTGLHF ADIDRLLAIL
HRLADQGETL VVIEHNLDVI ATADWVIDLG PDAGGNGGRI VAMGPPDAIA KSPESLTGRY
LNDRPPK
//
