ID A0A1U7D8W7_9RHOB Unreviewed; 766 AA.
AC A0A1U7D8W7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Ga0080559_TMP3783 {ECO:0000313|EMBL:APX24579.1};
OS Salipiger profundus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Salipiger.
OX NCBI_TaxID=1229727 {ECO:0000313|EMBL:APX24579.1, ECO:0000313|Proteomes:UP000186559};
RN [1] {ECO:0000313|EMBL:APX24579.1, ECO:0000313|Proteomes:UP000186559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JLT2016 {ECO:0000313|EMBL:APX24579.1,
RC ECO:0000313|Proteomes:UP000186559};
RA Tang K.;
RT "Deep-sea bacteria in the southern Pacific.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP014796; APX24579.1; -; Genomic_DNA.
DR RefSeq; WP_076624403.1; NZ_FOLR01000001.1.
DR AlphaFoldDB; A0A1U7D8W7; -.
DR STRING; 1229727.Ga0080559_TMP3783; -.
DR KEGG; tpro:Ga0080559_TMP3783; -.
DR Proteomes; UP000186559; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:APX24579.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000186559};
KW Transferase {ECO:0000313|EMBL:APX24579.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 402..625
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 649..765
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 700
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 766 AA; 83244 MW; 167992FC74CB4005 CRC64;
MTEFAAKLQH DRGRAFGFLR GAGILLALAS LCALLSVQKD GTGLGVALVT AAAAFAAMAV
LLAATAGLRR YRTALEIETI HRLAEDSATP IMVTNRAQTV IVANAAARQQ FGEVRGGGLP
QILGRSIVSA DAVLRRLDDL ASEQGFARES VSTHTDRFKL SVRRLARGHG LWRIEAGLTP
PETEPEIDEP PVLTLGRSGA VLFMNGRARS MLGRRIKQLD DVLEDPPLHP GREHGFRTPQ
GTRRFIARCL EAGIGRQELV LDPVAAEDDA PEAPSGFDDL PVPLLRLDRD GTILRANAVA
CRLLDTASAD GRNIAEFMEG LGRSIQGWLG EAAVGRGLQR SEFLRLARSD REVFVQVTLN
RVRVGGKSEL VAVLNDATEL KTLEAQFVQS QKMQAIGQLA GGVAHDFNNL LTAISGHCDL
LLLRHDQGDP DYADLVQINQ NANRAAALVG QLLAFSRKQT LRPELLDLRD TLSDLTHLLN
RLVGEKIELT LSHDPVLPAI RGDRRQLEQV LMNLVVNARD AMPDGGTIRI ETERRLLLEP
LKRDRAMVEP GEYASVKVSD AGVGIAQDSL QKVFEPFYTT KRTGEGTGLG LSTVYGIVKQ
TGGFIFVDST PDEGSCFTLL FPAYTPPVGA EVPPRPPERR RMPRAGSGVV LLVEDEAPVR
AFAARALRMR GYTVLEAASA EEALETLSDD AVSVDVFVTD VIMPGMDGPT WVNEALKARP
DTRVVFVSGY AEDMFEEGTE RVPESVFLPK PFSLSQLTET VHQQMT
//
