ID A0A1U7DEM5_9RHOB Unreviewed; 234 AA.
AC A0A1U7DEM5; A0A2M9DH96;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase {ECO:0000313|EMBL:APX88460.1};
GN ORFNames=BV394_00890 {ECO:0000313|EMBL:APX88460.1}, CLV77_1633
GN {ECO:0000313|EMBL:PJJ87069.1};
OS Brevirhabdus pacifica.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Brevirhabdus.
OX NCBI_TaxID=1267768 {ECO:0000313|EMBL:APX88460.1, ECO:0000313|Proteomes:UP000187266};
RN [1] {ECO:0000313|EMBL:APX88460.1, ECO:0000313|Proteomes:UP000187266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DY6-4 {ECO:0000313|EMBL:APX88460.1,
RC ECO:0000313|Proteomes:UP000187266};
RA Wang X.;
RT "Genomic analysis of Xuhuaishuia manganoxidans DY6-4.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PJJ87069.1, ECO:0000313|Proteomes:UP000229573}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 27767 {ECO:0000313|EMBL:PJJ87069.1,
RC ECO:0000313|Proteomes:UP000229573};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): From Individual Species to Whole Genera.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP019124; APX88460.1; -; Genomic_DNA.
DR EMBL; PGFI01000011; PJJ87069.1; -; Genomic_DNA.
DR RefSeq; WP_076978484.1; NZ_PGFI01000011.1.
DR AlphaFoldDB; A0A1U7DEM5; -.
DR STRING; 1267768.BV394_00890; -.
DR OrthoDB; 9803687at2; -.
DR Proteomes; UP000187266; Chromosome.
DR Proteomes; UP000229573; Unassembled WGS sequence.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02070; corrinoid_protein_B12-BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR036594; Meth_synthase_dom.
DR PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR SMART; SM01018; B12-binding_2; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF47644; Methionine synthase domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51337; B12_BINDING_NTER; 1.
PE 4: Predicted;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:APX88460.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000187266};
KW Transferase {ECO:0000313|EMBL:APX88460.1}.
FT DOMAIN 9..103
FT /note="B12-binding N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51337"
FT DOMAIN 103..234
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 234 AA; 25329 MW; E5A66A4B234B4330 CRC64;
MADEEEDIIL SELNDEELVQ QMFDDLYDGL REEIEEGVNI LLERGWEPYR VLTEALVGAM
TIVGNDFRDG ILFVPEVLLA ANAMKGGMAI LKPLLVETGA PRMGKMVIGT VKGDIHDIGK
NLVAMMMEGA GFEVVDLGIN NAADAYIDAL IAEEADILGM SALLTTTMPY MKTVIDQLAE
KGIRDDYIVL VGGAPLNEEF GKAIGADAYC RDAAVAVETA KDFISRKHNQ MAAG
//
