ID A0A1U7DN84_9FLAO Unreviewed; 310 AA.
AC A0A1U7DN84;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU003915};
DE EC=5.2.1.8 {ECO:0000256|RuleBase:RU003915};
GN ORFNames=BWZ22_01380 {ECO:0000313|EMBL:APY09977.1};
OS Seonamhaeicola sp. S2-3.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae.
OX NCBI_TaxID=1936081 {ECO:0000313|EMBL:APY09977.1, ECO:0000313|Proteomes:UP000187101};
RN [1] {ECO:0000313|EMBL:APY09977.1, ECO:0000313|Proteomes:UP000187101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S2-3 {ECO:0000313|EMBL:APY09977.1,
RC ECO:0000313|Proteomes:UP000187101};
RA Chi W.-J., Kim J.H.;
RT "Complete genome sequence of Seonamhaeicola sp. S2-3 isolated from seawater
RT in Jeju island.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC ChEBI:CHEBI:83834; EC=5.2.1.8;
CC Evidence={ECO:0000256|ARBA:ARBA00000971, ECO:0000256|PROSITE-
CC ProRule:PRU00277, ECO:0000256|RuleBase:RU003915};
CC -!- SIMILARITY: Belongs to the FKBP-type PPIase family.
CC {ECO:0000256|RuleBase:RU003915}.
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DR EMBL; CP019389; APY09977.1; -; Genomic_DNA.
DR RefSeq; WP_076697518.1; NZ_CP019389.1.
DR AlphaFoldDB; A0A1U7DN84; -.
DR STRING; 1936081.BWZ22_01380; -.
DR KEGG; seon:BWZ22_01380; -.
DR OrthoDB; 9807797at2; -.
DR Proteomes; UP000187101; Chromosome.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR CDD; cd00317; cyclophilin; 1.
DR Gene3D; 3.10.50.40; -; 1.
DR Gene3D; 2.40.100.10; Cyclophilin-like; 1.
DR InterPro; IPR029000; Cyclophilin-like_dom_sf.
DR InterPro; IPR020892; Cyclophilin-type_PPIase_CS.
DR InterPro; IPR002130; Cyclophilin-type_PPIase_dom.
DR InterPro; IPR044666; Cyclophilin_A-like.
DR InterPro; IPR046357; PPIase_dom_sf.
DR InterPro; IPR001179; PPIase_FKBP_dom.
DR PANTHER; PTHR45625; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED; 1.
DR PANTHER; PTHR45625:SF4; PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00254; FKBP_C; 1.
DR Pfam; PF00160; Pro_isomerase; 1.
DR PRINTS; PR00153; CSAPPISMRASE.
DR SUPFAM; SSF50891; Cyclophilin-like; 1.
DR SUPFAM; SSF54534; FKBP-like; 1.
DR PROSITE; PS00170; CSA_PPIASE_1; 1.
DR PROSITE; PS50072; CSA_PPIASE_2; 1.
DR PROSITE; PS50059; FKBP_PPIASE; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|PROSITE-ProRule:PRU00277,
KW ECO:0000256|RuleBase:RU003915};
KW Reference proteome {ECO:0000313|Proteomes:UP000187101};
KW Rotamase {ECO:0000256|ARBA:ARBA00023110, ECO:0000256|PROSITE-
KW ProRule:PRU00277}.
FT DOMAIN 14..148
FT /note="PPIase cyclophilin-type"
FT /evidence="ECO:0000259|PROSITE:PS50072"
FT DOMAIN 222..310
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
SQ SEQUENCE 310 AA; 33413 MW; 4AD9B37EDDC1056B CRC64;
MQDGLYAKFN TTKGEILVAL EYKKTPGTVG NFVALAEGNL ENAVKPQGTP YYDGLKFHRV
IPDFMIQGGC PQGTGTGNPG YQFDDEFHPD LKHDGPGVLS MANAGPGTNG SQFFITHVET
PWLDNNHTVF GKVTEGQDVV DAIAQGDTIE TLEILRVGAE AEAFNAVEAF RTFEGAREKR
EAEAKAKAET ELDKLAAGFE KTESGLRYQI IQKGDGAKPE KGKTVSVHYK GQLADGTVFD
SSYKRNQPID FPIGVGQVIP GWDEGIQLLN VGDKARLVIP SHLGYGSRGA GGVIPPNATL
IFDVELMNVK
//
